Published April 3, 2025
| Version v1
Dataset
Open
Female summary statistics from "Role of X chromosome and dosage compensation mechanisms in complex trait genetics"
Authors/Creators
Description
Full female summary statistics generated in "Role of X chromosome and dosage compensation mechanisms in complex trait genetics".
For UK biobank (UKB), GWAS were performed using BOLT-LMM v2.3.2. The files contain the following columns:
- SNP: rs number or ID string
- CHR: chromosome
- BP: base pair position mapped to assembly GRCh37
- GENPOS: genetic position either from bim file or interpolated from genetic map
- ALLELE1: first allele in bim file (usually the minor allele), used as the effect allele
- ALLELE0: second allele in bim file, used as the reference allele
- A1FREQ: frequency of first allele
- F_MISS: frequency of first allele
- CHISQ_LINREG: standard linear regression chi-square statistics
- P_LINREG: standard linear regression p-value
- BETA: effect size from BOLT-LMM approximation to infinitesimal mixed model
- SE: standard error of effect size
- CHISQ_BOLT_LMM_INF: infinitesimal mixed model association test chi-square statistics
- P_BOLT_LMM_INF: infinitesimal mixed model association test p-value
- CHISQ_BOLT_LMM: non-infinitesimal mixed model association test chi-square statistics
- P_BOLT_LMM: non-infinitesimal mixed model association test p-value
For FinnGen R10 (FG), GWAS were performed using REGENIE v2.2.4 pipeline. The files contain the following columns:
- #chrom: chromosome
- pos: base pair position mapped to assembly GRCh38
- ref: reference allele
- alt: alternative allele
- pval: analysis p-value
- mlogp: -log10(p-value)
- beta: effect size of alternate allele
- sebeta: standard error of effect size
- af_alt: allele frequency of the alternative allele
Files
Files
(39.6 GB)
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