Published January 15, 2025 | Version v1
Dataset Open

GEX and ATAC count matrices for pEM040 sgRNA singlets

  • 1. Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center
  • 2. Tri-Institutional Training Program in Computational Biology & Medicine

Description

AnnData objects containing gene expression and ATAC tile matrices for 4,724 cells assigned exactly one sgRNA, using sgRNA expression vector pEM040. Gene expression AnnData can be analyzed with Scanpy; ATAC AnnData can be analyzed with SnapATAC2. These datasets were analyzed to produce results and figures in Metzner*, Southard* et al., Cell Systems 2025.

Files

Files (2.6 GB)

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md5:fd8f4660146353a6ee5ff0f1cf4fe913
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md5:79cc85ccf50a2a7d7d46e8a493a26258
107.9 MB Download

Additional details

Related works

Is supplement to
Publication: 10.1016/j.cels.2024.12.002 (DOI)

Dates

Available
2025-01-15