Published March 21, 2025 | Version v1
Dataset Open

Spatial patterning of fibroblast TGFβ signaling underlies treatment resistance in rheumatoid arthritis - Xenium data (in vitro co-culture)

Authors/Creators

  • 1. ROR icon Brigham and Women's Hospital

Description

Xenium spatial transcriptomics datasets for 1) RA synovial tissue biopsies for 17 patients pre- and post-treatment (5101 gene probes, 5k panel+), 2) RA synovial tissue biopsies for 4 patients (50 probes, custom panel), 3) 2D in vitro co-culture system of synovial fibroblasts and endothelial cells (50 probes, custom panel). 

This batch of data corresponds to: 3) in vitro co-culture data. 

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md5:a811a493664ca561319e5b405b92e723
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Additional details

Related works

Is described by
Preprint: 10.1101/2025.03.14.642821 (DOI)