Ten simple rules to build sustainable bioinformatics capacity using Nextflow and nf-core with a focus on early-mid career researchers: The Kids Research Institute Australia, case report.
Authors/Creators
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Agudelo-Romero, Patricia
(Project leader)1
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Conradie, Talya
(Researcher)1
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Caparros-Martin, Jose A
(Researcher)1
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Martino, David J
(Researcher)1
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Kicic, Anthony
(Researcher)1
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Stick, Stephen M.
(Researcher)2
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Hakkaart, Christopher
(Researcher)3
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Sharma, Abhinav
(Researcher)4
- Theme Collaboration Group (Other)
- 1. Wal-Yan Respiratory Research Centre, The Kids Research Institute Australia, 6009, Perth, Western Australia, Australia.
- 2. Department of Respiratory and Sleep Medicine, Perth Children's Hospital, 6009, Perth, Western Australia, Australia.
- 3. Seqera, Carrer de Maria Aguilo, 28, Barcelona, 08005, Spain.
- 4. DSI-NRF Centre of Excellence for Biomedical Tuberculosis Research; SAMRC Centre for Tuberculosis Research; Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, 7505, Cape Town, Western Cape, South Africa.
Description
The increasing adoption of high-throughput "omics" technologies has heightened the demand for standardized, scalable, and reproducible bioinformatics workflows. Nextflow and nf-core provide a robust framework for researchers, particularly early- and mid-career researchers (EMCRs), to navigate complex data analysis. At The Kids Research Institute Australia, we implemented a structured approach to bioinformatics capacity building using these tools. This paper presents ten practical rules that facilitated the successful adoption of Nextflow and nf-core, addressing implementation, knowledge gaps, resource allocation, and community support. Our experience serves as a guide for institutions aiming to establish sustainable bioinformatics capabilities and empower EMCRs.
Files
TenRules_Bioinfo_Nextflow_NFcore_Figure1.pdf
Additional details
Dates
- Submitted
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2025-03-18