Code Release for Froemel et al., 2025

Joint release for the github repositories accompanying the Manuscript Frömel et al., Design principles of cell state specific enhancers in hematopoiesis (2025)

For updates, see the github pages:

github.com/veltenlab/MPRA_figures : Code to reproduce the figures of the manuscript. Authors: Robert Frömel and Lars Velten

github.com/veltenlab/MPRAscripts : snakemake pipeline for processing raw lenti-MPRA sequencing data. Author: Robert Frömel

github.com/veltenlab/MPRA_prediction : Deep learning model. Also contains code describing the model-guided design of new sequences, and code used to place transcription factor binding sites on random DNA. Authors: Felix Pacheco-Pastor, Robert Frömel and Lars Velten

github.com/theobiolab/MPRAfitting : Biophysical model. Author: Rosa Martinez-Corral