Published March 10, 2025 | Version v1
Conference paper Open

INDICATORS OF TOTAL IMMUNOGLOBULINS IN PATIENTS WITH ARTHROTIC ARTHRITIS

Authors/Creators

  • 1. 1Bukhar State Medical Institute
  • 2. 2Human Immunology and Genomics Institute
  • 3. 3Republican Children's Neuropsychiatric Hospital named after U.K. Kurbanov
  • 4. 4National Rehabilitation Center for the Disabled and Prosthetics

Description

The work included a comprehensive laboratory examination of patients with different stages of knee osteoarthritis. The patterns of metabolic disorders in patients with osteoarthritis in the form of activation of the prooxidant system and inhibition of the enzymatic link of antioxidant protection were revealed. It was shown that the degree of oxidative stress clearly correlates with the severity of clinical manifestations of osteoarthritis. The most clinically significant blood parameters for laboratory diagnostics of this pathology were identified, such as aliphatic aldehyde groups of oxidized proteins and paraoxanase activity.

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References

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