Published February 14, 2025 | Version v1

The Impact of Polycystic Ovary Syndrome (PCOS) on Metabolic and Cardiovascular Health

  • 1. Assistant of the Department of Obstetrics and Gynecology No.3
  • 2. 1st year clinical resident

Description

Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting women of reproductive age. Characterized by hormonal imbalances, irregular ovulation, and metabolic disturbances, PCOS is not only a reproductive disorder but also a significant risk factor for cardiovascular disease (CVD) and type 2 diabetes. This article examines the metabolic consequences of PCOS, including insulin resistance, dyslipidemia, obesity, and hypertension, and discusses current and emerging therapeutic strategies.

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References

  • 1. Azziz, R., Carmina, E., Chen, Z., et al. (2016). "Polycystic ovary syndrome." Nature Reviews Disease Primers, 2, 16057.
  • 2. Escobar-Morreale, H. F. (2018). "Polycystic ovary syndrome: Definition, aetiology, diagnosis and treatment." Nature Reviews Endocrinology, 14(5), 270-284.
  • 3. Moran, L. J., Misso, M. L., Wild, R. A., & Norman, R. J. (2010). "Impaired glucose tolerance, type 2 diabetes and metabolic risk in PCOS: A systematic review and meta-analysis." Human Reproduction Update, 16(4), 347-363.