Development and Validation of a UV- Visible Spectrophotometric Method for Quantitative Analysis of Valsartan in Bulk and Tablet Dosage Forms

Objectives:A novel, cost-effective UV spectrophotometric method was developed for the quantification of Valsartan in pure and tablet forms. Method: The analysis utilized methanol as the solvent, with a wavelength of 260 nm, using a Systronics 2201 UV-Visible double beam spectrophotometer. The method was validated per ICH guidelines. Results: Validation included parameters such as linearity (10-50 µg/ml), accuracy (recovery between 98.5% and 99.7%), precision, robustness, limit of detection (LOD), and limit of quantification (LOQ). The percentage relative standard deviation (%RSD) was below acceptable limits. Conclusion: The developed UV spectroscopic method is accurate, precise, stable, linear, specific, and simple, making it suitable for routine analysis of Valsartan in both bulk and tablet forms.