Published February 2, 2025 | Version v1

PROTAC-induced Protein Structural Dynamics in Targeted Protein Degradation

Authors/Creators

  • 1. ROR icon University of California, Riverside

Description

Initial conformations (.pdb) of each degredation machinary complex (dbet1, dbet23, dbet57, and dbet70) is provided here. 

 

Due to the large file size, trajectories (.dcd) and topology (.prmtop) file of each degredation machinary complex are provided through the link below: 

https://drive.google.com/drive/folders/1BVsIOcurCji0-E6b8cvax_22XAG0pvV-?usp=drive_link

 

Files

Files (13.7 MB)

Name Size Download all
md5:deeeaf80b0b6165b958048b5edc8e16c
3.4 MB Download
md5:850c8cc074b776e0e98be6d88c2de029
3.4 MB Download
md5:0cb8578647549f4ff40c2fcb06de1ad5
3.4 MB Download
md5:f36d8ae2a41bd793fa49d2e7c3346722
3.4 MB Download

Additional details

Additional titles

Subtitle
PDB file of Degradation Machinery Complex

Related works

Is supplement to
Journal article: 10.7554/eLife.101127.2 (DOI)

Dates

Available
2025-02-03