Published September 27, 2016 | Version v1
Poster Open

"VEGFR2 blockade in murine atherosclerotic vein grafts enhances plaque stability and reduces intraplaque haemorrhage by enhancement of plaque neovessel maturation"

Description

Blockade of VEGFR2 normalizes the unbridled process of plaque neovessel formation and induces maturation of nascent vessels resulting in prevention of intraplaque haemorrhage and influx of inflammatory cells into the plaque and subsequently increases plaque stability.

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Additional details

Funding

European Commission
MOGLYNET - Modulation of glycolytic flux as a new approach for treatment of atherosclerosis and plaque stabilization: a multidisciplinary study 675527