A Review On Trigonella Foenum-Graceum Linn (Fenugreek)

ABSTRACT

The goal of the current work is to use the wet granulation technology to make medication tablets using fenugreek extract. Additionally, research was done on the impact of sodium starch glycolate, a super disintegrant, on drug release and disintegration. Mucilage found in fenugreek extract slows down the disintegration of tablets, resulting in a slower release of the medication. Therefore, sodium starch glycolate was employed as a super disintegrant to enhance disintegration and, consequently, in vitro drug release. Wet granulation was used to make tablet formulations both with and without sodium starch glycolate. It was done to evaluate the granules' flow characteristics and characterize the physicochemical makeup of tablet formulations. The fundamental cause of fenugreek's antidiabetic effect is the alkaloid trigonelline, which is present in large amounts. For the treatment of diabetes, this study concludes that fenugreek seed extracts in tablet form with super disintegrants will be more desirable, useful, and therapeutically more effective than combining the plant components directly for a quicker commencement of action.

Keywords: Tablet; sodium starch glycolate; fenugreek.