Published January 17, 2021 | Version v1
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Synthesis, Characterization and Antimicrobial Activity of Some 4, 5- Dihydro. 3, 5- Diaryl- N- [(Arylamido/Imido)- Alkyl] Pyrazole- 1- Carbothioamides/Carboxamides

  • 1. Department of chemistry, Unversity of Lucknow, Lucknow (U.P.), India
  • 2. Division of Microbiology, Cental Drug Research Institute (CDRI), Lucknow (U.P.), India

Description

Synthesis of substituted pyrazoles derivatives was undertaken employing a convenient and easily accessible procedure. In this article some 4, 5- dihydro- 3, 5- diaryl- N- [(anylamidolimido) alkyl] pyrazole- 1- carbothrioamides/carboxamides were synthesized from 1, 3- diaryl- prop- 2- enes as starting material for their characterization and antimicrobial activity involving five fungal and four bacterial strain in vitro. Synthesized substituted pyrazole compounds were obtained in the yields varying 53-68%.

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synthesis-characterization-and-antimicrobial-activity-of-some-4-5-dihydro-3-5-diaryl-n-arylamidoimido-alkyl-pyrazole-1-c.pdf