Dynamic spatiotemporal activation of neurogenic competence in striatal mouse astrocytes_2024
Authors/Creators
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1.
University of Turin
- 2. Neuroscience Institute Cavalieri Ottolenghi
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3.
University of Southampton
Description
The University of Turin (UniTo) released the "Fogli Nato et al., 2024_Stem Cell Reports_Dataset" containing all the results from the following publication: https://www.sciencedirect.com/science/article/pii/S2213671124002455?via%3Dihub (corresponding author: Prof. Federico Luzzati, federico.luzzati@unito.it).
This work received fundamental contribution from NSC-Reconstruct fundings (874758; https://cordis.europa.eu/project/id/874758/reporting; https://www.nsc-reconstruct.com/en/index.do) to Prof. Annalisa Buffo.
Results were obtained from histological ex vivo brain samples from a mouse model of excitotoxic lesion-induced striatal neurogenesis. Data were obtained with multiple techniques, including BrdU incorporation experiments, genetic lineage tracing and clonal analysis. Cells were quantified from confocal microscopy images and 3D reconstructions obtained from serial sections.
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Additional details
Related works
- Is published in
- Journal article: 10.1016/j.stemcr.2024.08.006 (DOI)
Funding
- European Commission
- NSC-Reconstruct (Novel Strategies for Cell-based Neural Reconstruction) 874758
- Ministry of Education, Universities and Research
- PNRR MUR – M4C2 – Investimento 1.4
- University of Turin
- Funds of the University of Turin and Compagnia di San Paolo (S1618 grant) S1618 grant
- Ministry of Education, Universities and Research
- ‘‘Dipartimenti di Eccellenza" 2018–2022 and 2023–2027
Dates
- Created
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2024-01-15
References
- Fogli M, Nato G, Greulich P, Pinto J, Ribodino M, Valsania G, Peretto P, Buffo A, Luzzati F. Dynamic spatiotemporal activation of a pervasive neurogenic competence in striatal astrocytes supports continuous neurogenesis following injury. Stem Cell Reports. 2024 Oct 8;19(10):1432-1450. doi: 10.1016/j.stemcr.2024.08.006. Epub 2024 Sep 19. PMID: 39303706; PMCID: PMC11561465.