Successful Treatment of Periodic Catatonia with Aripiprazole : A Case Report and Review of Treatment

Periodic catatonia is a rare and challenging psychiatric syndrome characterized by recurrent episodes of motor disturbances. Understanding its management remains critical for improving patient outcomes. We hereby present a case of 20-year-old male who presented with recurrent periodic catatonia unresponsive to benzodiazepines and sensitive to standard antipsychotics. In this patient transitioning to aripiprazole at a low dose resulted in significant improvement, with no further hospitalizations or adverse effects. The case highlights the role of aripiprazole, a partial dopamine agonist, in managing refractory catatonia. Its efficacy, supported by similar cases in the literature, emphasizes its utility as an individualized treatment option. Aripiprazole offers a promising therapeutic alternative for periodic catatonia underscoring the importance of tailored interventions in achieving optimal outcomes.