Published June 2, 2025 | Version 1
Dataset Open

OCTAVE Dataset: Optical Coherence Tomography Annotated Volume Experiment

Description

This is a large dataset of OCT 3D image volumes and pixel-level segmentation labels for the development of an deep learning model to autonomously detect and identify anatomic and pathological features of the retina.

This project was described in the paper:

“Identifying Retinal Features Using a Self‑Configuring CNN for Clinical Intervention”
Daniel S. Kermany, Wesley Poon, Anaya Bawiskar, Natasha Nehra, Orhun Davarci, Glori Das, Matthew Vasquez, Shlomit Schaal, Raksha Raghunathan & Stephen T. C. Wong Invest. Ophthalmol. Vis. Sci., June 2, 2025; PMID 40525921

Instructions for using this dataset or replicating the results of the paper can be found on the OCTAVE GitHub page
 
This dataset is made available for use in research only. Use of this dataset requires appropriate citation of both this dataset (DOI: 10.5281/zenodo.14580071) and the associated paper (DOI: 10.1167/iovs.66.6.55).
 
Important: Ensure you are using the latest version of this dataset, if multiple versions available

Acknowledgments
Supported by the National Eye Institute F31EY037177 (D.S.K.)
National Cancer Institute R01CA288613 (S.T.C.W.)
National Cancer Institute R01NS140292 (S.T.C.W.)
T.T. and W.F. Chao Foundation (S.T.C.W.)
John S. Dunn Research Foundation (S.T.C.W.)
Johnsson Estate (S.T.C.W.). 

Files

OCTAVE.zip

Files (1.2 GB)

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Additional details

Related works

Is supplement to
Journal article: 10.1167/iovs.66.6.55 (DOI)

Funding

National Eye Institute
Optical Coherence Tomography (OCT)-Guided Ultrafast, Nonthermal Laser Microablation for Non-invasive Vitreoretinal Surgery F31EY037177
National Cancer Institute
Advancing Thyroid Cancer Diagnostics with AI-enhanced Multimodal Optical Histopathology R01CA288613
National Cancer Institute
DeepStroke+: An Advanced Mobile AI Diagnostic Tool for Fast and Precise Detection of Acute Strokes in Mobile Stroke Units, Emergency Rooms, and Telestroke Triage R01NS140292
John S. Dunn Foundation

Software

Repository URL
https://github.com/Translational-Biophotonics-Laboratory/octvision3d
Programming language
Python
Development Status
Active

References

  • Kafieh R, Rabbani H, Abramoff MD, Sonka M. Intra-retinal layer segmentation of 3D optical coherence tomography using coarse grained diffusion map. Med Image Anal. 2013; 17(8): 907–928.
  • Rasti R, Rabbani H, Mehridehnavi A, Hajizadeh F. Macular OCT classification using a multi-scale convolutional neural network ensemble. IEEE Trans Med Imaging. 2018; 37(4): 1024–1034.
  • Stankiewicz A, Marciniak T, Dabrowski A, Stopa M, Marciniak E, Obara B. Segmentation of preretinal space in optical coherence tomography images using deep neural networks. Sensors. 2021; 21(22): 7521.
  • Tian J, Varga B, Somfai GM, Lee W-H, Smiddy WE, Cabrera DeBuc D. Real-time automatic segmentation of optical coherence tomography volume data of the macular region. PLoS One. 2015; 10(8): e0133908.