Published July 11, 2024 | Version v1
Publication Open

Efficacy of Photodynamic Therapy Combined With Scaling And Root Planning In The Treatment Of Chronic Periodontitis: A Systematic Literature Review.

Authors/Creators

  • 1. Dentist, Universidad Central del Ecuador

Contributors

  • 1. Dentist, Independent Investigator.
  • 2. Dentist, Universidad Tecnológica Equinoccial De Quito.
  • 3. Dentist, Universidad de las Américas.

Description

Chronic periodontitis (CP) is a prevalent inflammatory disease-causing tooth loss, significantly impacting physical and mental health. A significant contributor to the development of CP and the resulting severe periodontal tissue destruction is dental plaque biofilm. Scaling and root planing (SRP) and antibiotics are standard treatments, although they have drawbacks and may lead to bacterial resistance. Using SRP in conjunction with photodynamic treatment (PDT) to treat cerebral palsy (CP) was evaluated in this integrative review. PDT, SRP, and CP-related search phrases were utilised in Scopus, Google Scholar, and PubMed to find papers published between 2019 and 2024. English-language research using human subjects that assessed PDT using SRP met the inclusion requirements. Research that lacked validity or significance were excluded. Probing pocket depth, clinical attachment levels, bleeding on probing, and plaque ratings were all significantly improved with PDT+SRP, according to clinical data from main investigations. Beneficial bacteria increased but periodontopathogens decreased in the microbial makeup. Although the long-term advantages of PDT+SRP were less evident, meta-analyses supported its effectiveness, especially in the short term. PDT therefore shows significant short-term benefits in microbial profiles and clinical outcomes in CP patients when used as an adjuvant to SRP. To verify long-term advantages and improve treatment regimens, further investigation is required.

Files

01.pdf

Files (373.1 kB)

Name Size Download all
md5:b93ec1fc3f1b82155e7e1ef8728ff49c
373.1 kB Preview Download

Additional details

References

  • A. C. R. Tanner, "Anaerobic culture to detect periodontal and caries pathogens," J. Oral Biosci., vol. 57, no. 1, pp. 18–26, Feb. 2015, doi: 10.1016/j.job.2014.08.001.
  • M. Wainwright and K. B. Crossley, "Photosensitising agents - Circumventing resistance and breaking down biofilms: A review," Int. Biodeterior. Biodegrad., vol. 53, no. 2, pp. 119–126, 2004, doi: 10.1016/j.ibiod.2003.11.006.
  • J. Song, Z. Gao, and M. Li, "Efficacy of adjunctive photodynamic therapy for chronic periodontitis undergoing scaling and root Planing: A Meta-analysis of randomized controlled trials," Opt. Laser Technol., vol. 149, p. 107808, May 2022, doi: 10.1016/J.OPTLASTEC.2021.107808.
  • Z. Akram, M. A. Raffat, S. Saad Shafqat, S. Mirza, and S. Ikram, "Clinical efficacy of photodynamic therapy as an adjunct to scaling and root planing in the treatment of chronic periodontitis among cigarette smokers: A systematic review and meta-analysis," Photodiagnosis Photodyn. Ther., vol. 26, pp. 334–341, Jun. 2019, doi: 10.1016/J.PDPDT.2019.04.027.
  • G. Hill, C. Dehn, A. V. Hinze, M. Frentzen, and J. Meister, "Indocyanine green-based adjunctive antimicrobial photodynamic therapy for treating chronic periodontitis: A randomized clinical trial," Photodiagnosis Photodyn. Ther., vol. 26, pp. 29–35, Jun. 2019, doi: 10.1016/j.pdpdt.2019.02.019.
  • K. Joshi, C. S. Baiju, H. Khashu, and S. Bansal, "Clinical effectiveness of indocyanine green mediated antimicrobial photodynamic therapy as an adjunct to scaling root planing in treatment of chronic periodontitis- A randomized controlled clinical trial," Photodiagnosis Photodyn. Ther., vol. 29, p. 101591, Mar. 2020, doi: 10.1016/J.PDPDT.2019.101591.
  • A. Lertpimonchai, S. Rattanasiri, S. Arj-Ong Vallibhakara, J. Attia, and A. Thakkinstian, "The association between oral hygiene and periodontitis: a systematic review and meta-analysis," Int. Dent. J., vol. 67, no. 6, pp. 332–343, Dec. 2017, doi: 10.1111/idj.12317.
  • M. F. Elsadek and M. F. Farahat, "Effectiveness of photodynamic therapy as an adjunct to periodontal scaling for treating periodontitis in geriatric patients," Eur. Rev. Med. Pharmacol. Sci., vol. 26, no. 6, pp. 1832–1838, 2022, doi: 10.26355/eurrev_202203_28327.
  • M. Kreisler, H. Al Haj, and B. D'Hoedt, "Clinical efficacy of semiconductor laser application as an adjunct to conventional scaling and root planing," Lasers Surg. Med., vol. 37, no. 5, pp. 350–355, Dec. 2005, doi: 10.1002/LSM.20252.
  • C. Liu, L. Hou, M. Wong, and W. Lan, "Comparison of Nd:YAG Laser Versus Scaling and Root Planing in Periodontal Therapy," J. Periodontol., vol. 70, no. 11, pp. 1276–1282, Nov. 1999, doi: 10.1902/JOP.1999.70.11.1276.
  • G. Jori et al., "Photodynamic therapy in the treatment of microbial infections: Basic principles and perspective applications," Lasers Surg. Med., vol. 38, no. 5, pp. 468–481, Jun. 2006, doi: 10.1002/LSM.20361.
  • R. R. Allison, V. S. Bagnato, R. Cuenca, G. H. Downie, and C. H. Sibata, "The future of photodynamic therapy in oncology," Futur. Oncol., vol. 2, no. 1, pp. 53–71, Feb. 2006, doi: 10.2217/14796694.2.1.53.
  • R. R. De Oliveira et al., "The effect of a single episode of antimicrobial photodynamic therapy in the treatment of experimental periodontitis. Microbiological profile and cytokine pattern in the dog mandible," Lasers Med. Sci., vol. 26, no. 3, pp. 359–367, May 2011, doi: 10.1007/S10103-010-0864-Z.
  • S. Dalvi, S. Benedicenti, T. Sălăgean, I. R. Bordea, and R. Hanna, "Effectiveness of antimicrobial photodynamic therapy in the treatment of periodontitis: A systematic review and meta-analysis of in vivo human randomized controlled clinical trials," Pharmaceutics, vol. 13, no. 6, 2021, doi: 10.3390/PHARMACEUTICS13060836.
  • N. Derikvand, S. S. Ghasemi, H. Safiaghdam, H. Piriaei, and N. Chiniforush, "Antimicrobial Photodynamic Therapy with Diode laser and Methylene blue as an adjunct to scaling and root planning: A clinical trial," Photodiagnosis Photodyn. Ther., vol. 31, p. 101818, Sep. 2020, doi: 10.1016/J.PDPDT.2020.101818.
  • M. Nie et al., "Efficacy of photodynamic therapy as an adjunct to scaling and root planing on clinical parameters and microbial composition in subgingival plaque of periodontitis patients: A split-mouth randomized clinical trial," J. Periodontol., vol. 95, no. 6, pp. 535–549, Jun. 2024, doi: 10.1002/JPER.23-0195.
  • K. Gandhi, R. Pavaskar, E. Cappetta, and H. Drew, "Effectiveness of Adjunctive Use of Low-Level Laser Therapy and Photodynamic Therapy After Scaling and Root Planing in Patients with Chronic Periodontitis," Int. J. Periodontics Restorative Dent., vol. 39, no. 6, pp. 837–843, 2019, doi: 10.11607/prd.4252.
  • F. AlAhmari, H. B. Ahmed, A. A. Al-Kheraif, F. Javed, and Z. Akram, "Effectiveness of scaling and root planning with and without adjunct antimicrobial photodynamic therapy in the treatment of chronic periodontitis among cigarette-smokers and never-smokers: A randomized controlled clinical trial," Photodiagnosis Photodyn. Ther., vol. 25, pp. 247–252, Mar. 2019, doi: 10.1016/J.PDPDT.2019.01.006.
  • M. Muzaheed et al., "Effectiveness of single versus multiple sessions of photodynamic therapy as adjunct to scaling and root planing on periodontopathogenic bacteria in patients with periodontitis," Photodiagnosis Photodyn. Ther., vol. 32, p. 102035, Dec. 2020, doi: 10.1016/J.PDPDT.2020.102035.