Acute Liver Failure Complicating Pregnancy: A Multidisciplinary Approach to Management
Authors/Creators
- 1. MD, Department of Obstetrics and Gynecology, Isha Hospital, Vadodara, Gujarat
- 2. MD, DM, Department of Hepatology, International Gastro Institute, Isha Hospital, Vadodara, Gujarat
- 3. MD, FCCCM, Department of Critical Care Medicine, Isha Hospital, Vadodara, Gujarat
- 4. MD, DM, Nephrology
- 5. MD, DM, Neurology
- 6. MBBS, Department of Critical Care Medicine, Isha Hospital, Vadodara, Gujarat
Description
Acute liver failure (ALF) during pregnancy is a rare but life-threatening condition associated with high maternal and fetal morbidity and mortality. We present a case of a 22-year-old primigravida at 30 weeks gestation who developed ALF with concurrent HELLP syndrome, disseminated intravascular coagulation (DIC), acute kidney injury (AKI), and posterior reversible encephalopathy syndrome (PRES). Despite the complexity of the presentation, a multidisciplinary team comprising obstetricians, intensivist, hepatologist, nephrologist, and neurologist collaborated to provide timely and comprehensive management. This case underscores the importance of a coordinated approach to optimize maternal and neonatal outcomes in such challenging scenarios.
Abstract (English)
Acute liver failure (ALF) during pregnancy is a rare but life-threatening condition associated with high maternal and fetal morbidity and mortality. We present a case of a 22-year-old primigravida at 30 weeks gestation who developed ALF with concurrent HELLP syndrome, disseminated intravascular coagulation (DIC), acute kidney injury (AKI), and posterior reversible encephalopathy syndrome (PRES). Despite the complexity of the presentation, a multidisciplinary team comprising obstetricians, intensivist, hepatologist, nephrologist, and neurologist collaborated to provide timely and comprehensive management. This case underscores the importance of a coordinated approach to optimize maternal and neonatal outcomes in such challenging scenarios.
Files
IJPCR,Vol16,Issue10,Article243.pdf
Files
(274.4 kB)
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Additional details
Dates
- Accepted
-
2024-09-26
Software
- Repository URL
- http://impactfactor.org/PDF/IJPCR/16/IJPCR,Vol16,Issue10,Article243.pdf
- Development Status
- Active
References
- 1. Pandey C, Pandey V, Tandon M, Karna S. Acute liver failure in pregnancy: Challenges and management. Indian Journal of Anaesthesia. 2015;59(3):144. 2. Alexander V, Benjamin SJ, Subramani K, Sowmya Sathyendra, Goel A. Acute liver failure in pregnancy. Indian Journal of Gastroenterology. 2024 Apr 1;43(2):325–37.