Published December 2, 2024 | Version v1

NODES_Inndiana_D14_RM4_Biphenyl Amides as Dual-Targeting SOCE/DHODH Inhibitors

  • 1. ROR icon Università degli Studi del Piemonte Orientale "Amedeo Avogadro"

Contributors

Description

The patent application titled “Biphenyl Amides as Dual-Targeting SOCE/DHODH Inhibitors” (No. 102024000024384) describes novel biphenyl amides that can simultaneously modulate Store-Operated Calcium Entry (SOCE) and human dihydroorotate dehydrogenase (hDHODH) for the treatment of autoimmune, inflammatory, and chronic degenerative diseases, as well as neurodegenerative and multisystem inflammatory diseases associated with SOCE overactivation and DHODH pathway alterations.

Files

Deliverable_D14_INNDIANA_RM4_Ottobre2024_Patent application on dual-targeting SOCE-DHODH inhibitors.pdf