Published November 25, 2024 | Version 0.1.0

Live-cell STED dataset of mitochondria containing ground truth and corresponding low intensity noisy images

Description

The dataset was acquired as part of the manuscript "Denoising diffusion models for high-resolution microscopy image restoration". The dataset contains ground truth and low intensity STED images of mitochondria acquired in live U2-OS cells stably expressing TOM20 coupled to the dead mutant of HaloTag7 which was made fluorescent by using the exchangeable ligand Hy4 bound to the fluorophore SiR. 

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Additional details

Related works

Is supplement to
Preprint: 10.48550/arXiv.2409.12078 (DOI)

Funding

Deutsche Forschungsgemeinschaft
Major Research Instrumentation Programme INST 161/1020-1 FUGG
Deutsche Forschungsgemeinschaft
CRC 1177 259130777
Deutsche Forschungsgemeinschaft
GRK 2566 414985841