Prospective observational study to evaluate the association of various parameters associated with severity of acute pancreatitis
Authors/Creators
- 1. Senior Resident, Department of General Surgery, Madhubani Medical College and Hospital, Madhubani, Bihar, India
- 2. Assistant Professor, Department of General Surgery, JNMC AMU, Aligarh,India
- 3. Associate Professor, Department of General Surgery, Madhubani Medical College and Hospital, Madhubani, Bihar, India
Description
Aim: The aim of this study was to evaluate the parameters associated with severity of acute pancreatitis. Methods: This Prospective observational study was done in the Department of General Surgery, Madhubani Medical College and Hospital, Madhubani, Bihar, India, for 1 year. Total 80 patients diagnosed as acute pancreatitis on the basis of clinical signs, biochemical markers and radiological signs were included in this study. they were investigated by various blood investigations like haemoglobin, total leukocyte count, differential count, haematocrit, calcium, Blood urea nitrogen (BUN), arterial blood gas analysis, serum electrolytes, Random blood sugar (RBS), liver function tests, Lactate dehydrogenase (LDH), serum amylase, serum lipase, ultrasound abdomen and contrast Computed tomography (CT) for those indicated. The two commonly used scoring systems in our institution were also analysed viz. Ranson’s score and modified Glasgow score. Results: Majority cases were seen in between 40 to 50 years 30(37.5%). In our study the 56 cases were mild acute pancreatitis (70%), 15 cases were moderately severe acute pancreatitis (18.5%) and 9 cases severe acute pancreatitis (11.25%). In our study the majority of cases who presented with acute pancreatitis were of alcohol induced type, 56 (70%). Gall stone pancreatitis accounted for 14 (17.5%) cases. In our study 50 (62.5%) patients had diabetes mellitus, 32 (40%) had hypertension and 40 (50%) had dyslipidemia. Major co-morbidity was diabetes mellitus among the studied population. In our study the 38 cases were having a Body mass index (BMI) of 18.5 to 24.9 (47.5%) and 8 (10%) were having a BMI of above 30 and 34 (42.5%) had BMI between 18.5 to 19.9. Majority of the cases 56 (70%) who presented were having habit of consuming alcohol. 4 (5%) patients in our study died due to complications of severe acute pancreatitis. The mean BMI in those with mild acute pancreatitis was 25.47±0.21 (Standard error (SE)), moderately severe acute pancreatitis was 29.54±0.62 and severe acute pancreatitis was 29.87±1.67. Conclusion: One should not wait for any single scoring system to get scored for effective treatment. A diagnosis of pancreatitis should be made using clinical, laboratory and radiological means and treatment in the form of aggressive crystalloid resuscitation should be started with intensive care monitoring at the earliest.
Abstract (English)
Aim: The aim of this study was to evaluate the parameters associated with severity of acute pancreatitis. Methods: This Prospective observational study was done in the Department of General Surgery, Madhubani Medical College and Hospital, Madhubani, Bihar, India, for 1 year. Total 80 patients diagnosed as acute pancreatitis on the basis of clinical signs, biochemical markers and radiological signs were included in this study. they were investigated by various blood investigations like haemoglobin, total leukocyte count, differential count, haematocrit, calcium, Blood urea nitrogen (BUN), arterial blood gas analysis, serum electrolytes, Random blood sugar (RBS), liver function tests, Lactate dehydrogenase (LDH), serum amylase, serum lipase, ultrasound abdomen and contrast Computed tomography (CT) for those indicated. The two commonly used scoring systems in our institution were also analysed viz. Ranson’s score and modified Glasgow score. Results: Majority cases were seen in between 40 to 50 years 30(37.5%). In our study the 56 cases were mild acute pancreatitis (70%), 15 cases were moderately severe acute pancreatitis (18.5%) and 9 cases severe acute pancreatitis (11.25%). In our study the majority of cases who presented with acute pancreatitis were of alcohol induced type, 56 (70%). Gall stone pancreatitis accounted for 14 (17.5%) cases. In our study 50 (62.5%) patients had diabetes mellitus, 32 (40%) had hypertension and 40 (50%) had dyslipidemia. Major co-morbidity was diabetes mellitus among the studied population. In our study the 38 cases were having a Body mass index (BMI) of 18.5 to 24.9 (47.5%) and 8 (10%) were having a BMI of above 30 and 34 (42.5%) had BMI between 18.5 to 19.9. Majority of the cases 56 (70%) who presented were having habit of consuming alcohol. 4 (5%) patients in our study died due to complications of severe acute pancreatitis. The mean BMI in those with mild acute pancreatitis was 25.47±0.21 (Standard error (SE)), moderately severe acute pancreatitis was 29.54±0.62 and severe acute pancreatitis was 29.87±1.67. Conclusion: One should not wait for any single scoring system to get scored for effective treatment. A diagnosis of pancreatitis should be made using clinical, laboratory and radiological means and treatment in the form of aggressive crystalloid resuscitation should be started with intensive care monitoring at the earliest.
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IJPCR,Vol13,Issue5,Article11.pdf
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Additional details
Dates
- Accepted
-
2021-08-13
Software
- Repository URL
- http://impactfactor.org/PDF/IJPCR/13/IJPCR,Vol13,Issue5,Article11.pdf
- Development Status
- Active
References
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