Published June 10, 2026 | Version v45

Dataset for drevalpy

  • 1. Technische Universität München
  • 2. Freie Universität Berlin

Description

All preprocessing details can be found in https://github.com/daisybio/preprocess_drp_data
or at https://github.com/daisybio/drevalpy

Change in this version:

  • Removed TOYv1 and TOYv2 because they are now available from nf-core/test-datasets, and we don't want to maintain them at two sites.

Changes before:

  • Added pathway activity features (pathway_features.csv) and SMILES-vector drug embeddings (drug_smilesvec.csv) to all datasets (CCLE, CTRPv1, CTRPv2, GDSC1, GDSC2, BeatAML2, PDX_Bruna).
  • The pEC50s were shifted by -6 because of the code update -> now corrected.
  • Meta now contains the gene lists, so they don't have to be duplicated
  • 2 new datasets: BeatAML2 and PDX_Bruna
  • Corrected wrong original AUC values of CTRPv2
  • Added MolGNet model to meta
  • Updated gene lists: intersection gene lists now also intersect BeatAML2 and PDX_Bruna. Reduced gene lists only contain genes contained in all datasets. 

Files

CCLE.zip

Files (5.5 GB)

Name Size
md5:e76faf5a2cd41a38007892707e02d8b7
2.7 GB Preview Download
md5:6dc9ad77cdf832d9c4b5e065d6536b94
162.2 MB Preview Download
md5:ef7421ef7c23813b4b86bb7e00d2ce7c
366.7 MB Preview Download
md5:12b6b5dbfd16684a902f223eb6c7103d
407.1 MB Preview Download
md5:a3a6cc49ed57ba1c9b163e56b88cce2f
518.5 MB Preview Download
md5:a338d837e449538ff9726a9dcd02629f
546.9 MB Preview Download
md5:49dc16929c6baa2b5d75c508429fa11f
521.5 MB Preview Download
md5:9088853103ebaec9700bcf741d4ed13a
10.5 MB Preview Download
md5:ff1708e48b853e95bca19d1f33949c70
213.3 MB Download
md5:ee6d83e01b870a7fea8a76c1c6e6f1ec
49.6 MB Preview Download

Additional details

Related works

Is supplement to
Journal article: 10.1038/s41467-026-72903-w (DOI)