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Published October 25, 2024 | Version v1.5.0

zol

Description

Major updates:

  • Introduce cgcg for interactive network visualization of homologous instances of gene clusters.
  • Introduce domain-mode in zol. Uses pyhmmer to identify Pfam domains in CDS features in gene clusters to chop the CDS features up by domains and perform domain-centric analyses instead of protein-centric analyses. Identifies domain-ortholog groups (DOGs 🐶 ) Useful for dealing with gene clusters featuring ginormous genes, such as PKSs or NPRSs.
  • Introduce zol-scape a simple wrapper of BiG-SCAPE to run zol on each GCF it identified to complement visual views produced by CORASON.
  • Upgrade project organization by addition of pyproject.toml , adjust setup.py, and get rid of Rscript references. Rscripts are now created de novo within result directories allowing users to customize them as needed.

Minor updates:

  • correct extraction of phage instances which are annotated as entire contigs/scaffolds by geNomad in atpoc.
  • minimal-mode in the database downloading script now includes Pfam HMMs in addition to PGAP HMMs.

What's Changed

  • Update to v1.5.0 by @raufs in https://github.com/Kalan-Lab/zol/pull/78
  • Update CITATION.cff by @raufs in https://github.com/Kalan-Lab/zol/pull/79

Full Changelog: https://github.com/Kalan-Lab/zol/compare/v1.4.12...v1.5.0

Notes

If you use this software, please cite the zol preprint/manuscript.

Files

Kalan-Lab/zol-v1.5.0.zip

Files (6.7 MB)

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md5:3192041b11e35dc6f7094a3400bc694f
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Additional details

Related works

Is supplement to
Software: https://github.com/Kalan-Lab/zol/tree/v1.5.0 (URL)