Published October 21, 2024 | Version v2

Source code and experimental data of human brain tissue (visual cortex, corona radiata) for poro-viscoelastic parameter identification

  • 1. Friedrich-Alexander-Universität Erlangen-Nürnberg
  • 2. ROR icon Universitat Politècnica de Catalunya
  • 3. ROR icon International Center for Numerical Methods in Engineering
  • 4. ROR icon University of Glasgow
  • 5. ROR icon Graz University of Technology
  • 6. ROR icon Norwegian University of Science and Technology

Description

Computer code and experimental data that we used for our inverse parameter identification of poro-viscoelastic material parameters for two different brain regions: visual cortex (gray matter) and corona radiata (white matter). The experimental data comprises large-strain cyclic loading and compression/tension relaxation. For details see the corresponding publication: "Model-driven exploration of poro-viscoelasticity in human brain tissue: Be careful with the parameters!".

Further explanation regarding the specimen preparation, experimental setup, as well as the assignment of regions and governing regions can be found in Hinrichsen, J., Reiter, N., Bräuer, L. et al. Inverse identification of region-specific hyperelastic material parameters for human brain tissue. Biomech Model Mechanobiol (2023). https://doi.org/10.1007/s10237-023-01739-w.

The file "nonlinear-poro-viscoelasticity.cc" contains our C++ Finite Element code based on the open source library deal.II. It is accompanied by an exemplary parameter file.

Funding: The support from the German Research Foundation (Deutsche Forschungsgemeinschaft, DFG) through the grants BU 3728/1-1, BU 3728/3-1, STE 544/70-1 as well as through project number 460333672 CRC1540 Exploring Brain Mechanics is gratefully acknowledged.

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Additional details

Related works

References
Publication: 10.1007/s10237-023-01739-w (DOI)
Publication: 10.1016/j.cma.2020.113128 (DOI)
Publication: 10.3389/fmech.2021.708350 (DOI)
Publication: 10.3389/fbioe.2023.1143304 (DOI)

Funding

Deutsche Forschungsgemeinschaft
CRC1540 Exploring Brain Mechanics 460333672
Deutsche Forschungsgemeinschaft
Brainiacs BU 3728/1-1
Deutsche Forschungsgemeinschaft
Experiments, modelling and computational simulations to characterize the porous and viscous behaviour of human brain tissue BU 3728/3-1, STE 544/70-1