Published 2023 | Version v2
Poster Open

Studying the Relationship between Fusobacterium nucleatum and Oral Squamous Cell Carcinoma

Authors/Creators

  • 1. Precision Medicine Lab, CECOS-RMI
  • 2. Lahore Grammar School Defence, D.H.A, Lahore
  • 3. ROR icon Khyber Medical College
  • 4. Institute of Integrative Biosciences, CECOS University
  • 5. Centre for Genomic Sciences, Rehman Medical Institute
  • 6. Department of Bioengineering, University Of Engineering and Applied Sciences, Swat

Description

Various communities of microorganisms such as F. nucleatum P. gingivalis, and E. coli play a significant role in the onset of different cancers. F. nucleatum, is a gram-negative, opportunistic bacteria known to create favorable conditions for colorectal cancer (CRC) and possesses a potential risk in breast cancer, esophageal cancer, and Head and Neck Squamous Cell Carcinoma [1,2]. This study aims to identify factors in OSCC and CRC interacting with F. nucleatum, indicating overlapping mechanisms between them, in the onset of cancer.

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Additional details

References

  • 1) McIlvanna, E., Linden, G., Craig, S. G., Lundy, F., & James, J. (2021). Fusobacterium nucleatum and oral cancer: a critical review. BMC Cancer, 21(1).
  • 2) Sami, A., Elimairi, I., Stanton, C., Ross, R. P., & Ryan, C. A. (2020). The Role of the Microbiome in Oral Squamous Cell Carcinoma with Insight into the Microbiome–Treatment Axis. International Journal of Molecular Sciences, 21(21)