Published 2024
| Version v2
Poster
Open
Transcriptomic Insights into lncRNA-mediated Pathways in Medulloblastoma(MB) Subtypes
Authors/Creators
-
1.
Khyber Medical College
- 2. Precision Medicine Lab, CECOS-RMI
- 3. Institute of Integrative Biosciences, CECOS University
- 4. Centre for Genomic Sciences, Rehman Medical Institute
Description
MB has been classified into subgroups i.e. WNT, SHH, Group 3 and Group 4. The molecularly distinct groups also exhibit unique clinical, pathological, and prognostic features; for instance, WNT has the most favorable prognosis, while Group 3 has the worst outcomes among MBs. Long non-coding RNAs (lncRNAs) are non-coding yet vital in cellular function, development, and disease .
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Additional details
References
- 1) Joshi, P., Jallo, G., & Perera, R. J. (2020). In silico analysis of long non-coding RNAs in medulloblastoma and its subgroups. Neurobiology of disease, 141, 104873. https://doi.org/10.1016/j.nbd.2020.104873
- 2) Jin, L., Ji, J., Shi, L., Jin, S., & Pei, L. (2019). lncRNA HAND2-AS1 inhibits cancer cell proliferation, migration and invasion by downregulating ROCK1 in HPV-positive and negative cervical squamous cell carcinoma. Experimental and therapeutic medicine, 18(4), 2512–2518. https://doi.org/10.3892/etm.2019.7830
- 3) Zhang, H., Yao, B., Tang, S., & Chen, Y. (2019). LINK-A Long Non-Coding RNA (lncRNA) Participates in Metastasis of Ovarian Carcinoma and Upregulates Hypoxia-Inducible Factor 1 (HIF1α). Medical science monitor : international medical journal of experimental and clinical research, 25, 2221–2227. https://doi.org/10.12659/MSM.913609