Published 2024 | Version v1

The Hunt for Biological Semiconductors: using BLAST to search the known protein space for unknown diode-like proteins

  • 1. Precision Medicine Lab (CECOS RMI)
  • 2. Pak Turk Maarif International Schools and Colleges
  • 3. Centre for Genomic Sciences, Rehman Medical Institute
  • 4. Department of Bioengineering, University of Engineering and Applied Sciences
  • 5. Department of Bioengineering, University of Engineering and Applied Sciences, Swat, Pakistan

Description

There has been considerable speculation in recent years on the nature of the current carriers in the electrical conductivity of proteins [1]. Evans and Gergely concluded that dry proteins should be electronic semiconductors with an interband gap of about 3.0 eV [2]. A more recent study by Cantiello et al. (2024) suggested strong rectification in purified actin paracrystals with a nonlinear electrical conductance [3].

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References

  • Rosenberg, B. (1962). "Electrical Conductivity of Proteins." Nature, 193, 364–365.
  • Evans et al. (1949). "Biochimica et Biophysica Acta," 3, 188.
  • Cantiello et al. (2024). "Actin Paracrystals Display Double Schottky Diode-Like Electrical Behavior." Advanced Electronic Materials, 10, 2300144.