Published 2024
| Version v1
Poster
Open
Prototype Plastic Molds as a Frugal Alternative to 3D Bioprinting for Regenerative Medicine and Organoid Culture
Authors/Creators
- 1. Precision Medicine Lab (CECOS RMI)
- 2. Institute of Integrative Biosciences, CECOS University
- 3. Department of Bioengineering, University of Engineering and Applied Sciences, Swat, Pakistan
- 4. Centre for Genomic Sciences, Rehman Medical Institute Peshawar, Pakistan
Description
Regenerative medicine allowing the culture of viable tissues and organs relies on 3D bio-printing of a biomimicking hydrogel to support the cultured cells, and the creation of pores and vasculature within the gel construct [1]. However, high costs and the complexity of the technology used have prevented its adoption in Pakistan. Comparatively, plastic 3D printing is more easily available, highlighting it as a potential alternative.
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Additional details
References
- 1. Fang, Wenzhuo et al. "Hydrogels for 3D Bioprinting in Tissue Engineering and Regenerative Medicine: Current Progress and Challenges." International Journal of Bioprinting, vol. 9, no. 5, 759, 23 May 2023, doi:10.18063/ijb.759.
- 2. Pereira, R. F. and Bártolo, P. J. (2015). "3D Bioprinting of Photocrosslinkable Hydrogel Constructs." Journal of Applied Polymer Science, 132, 42458. doi:10.1002/app.42458.
- 3. Compaan, Ashley M et al. "Cross-Linkable Microgel Composite Matrix Bath for Embedded Bioprinting of Perfusable Tissue Constructs and Sculpting of Solid Objects." ACS Applied Materials & Interfaces, vol. 12, no. 7, (2020): 7855-7868. doi:10.1021/acsami.9b15451.
- 4. Song, Kaidong et al. "Injectable Gelatin Microgel-Based Composite Ink for 3D Bioprinting in Air." ACS Applied Materials & Interfaces, vol. 12, no. 20, (2020): 22453-22466. doi:10.1021/acsami.0c01497.