Published 2024 | Version v1
Poster Open

Gene Expression Profiling Of Pancreatic Ductal Adenocarcinoma Associated Diabetes Mellitus (PDAC-DM) With Pancreatic Ductal Adenocarcinoma (PDAC) And Diabetes Mellitus (DM)

Authors/Creators

  • 1. Khyber Girls Medical College (KGMC)
  • 2. Precision Medicine Lab, CECOS-RMI
  • 3. Institute of Integrative Biosciences, CECOS University
  • 4. Centre for Genomic Sciences, Rehman Medical Institute

Description

Pancreatic ductal adenocarcinoma(PDAC) is one of the commonly associated melignancy with Diabetes Mellitus and is referred to as Pancreatic ductal adenocarcinoma-associated diabetes(PDAC-DM). PDAC-DM has a 5-year average survival rate of less than 6%.

Objectives: 

  • To understand the progression of PDAC from DM
  • To identify differentially expressed genes that are unique toPDAC-DM
  • To explore pathways that are altered in the condition

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Additional details

References

  • Hu Y, Zeng N, Ge Y, Wang D, Qin X, Zhang W, Jiang F and Liu Y (2022) Identification of the Shared Gene Signatures and Biological Mechanism in Type 2 Diabetes and Pancreatic Cancer. Front. Endocrinol. 13:847760. doi: 10.3389/fendo.2022.847760