A Comparative Study of Injection Ferric Carboxy Maltose and Injection Iron Sucrose for Treatment of Iron Deficiency Anaemia in Pregnancy at Kamla Raja Hospital, Gwalior
Authors/Creators
- 1. Assistant Professor, Department of Obstetrics and Gynaecology, G.R. Medical College, Gwalior, Madhya Pradesh, India
- 2. Professor, Department of Obstetrics and Gynaecology, G.R. Medical College, Gwalior, Madhya Pradesh, India
- 3. Professor & HOD, Department of Obstetrics and Gynaecology, G.R. Medical College, Gwalior, Madhya Pradesh, India
Description
Background: Iron deficiency anaemia is the most common form of anaemia during pregnancy. It may have detrimental effects on the mother and growing foetus. There is need to study the effectiveness and safety of injection ferric carboxy maltose and injection iron sucrose in pregnant women havinganaemia. Aim: To carry out a comparative study of injection ferric carboxy maltose and injection iron sucrose for treatment of iron deficiency anaemia in pregnancy at Kamla Raja Hospital, Gwalior. Methods and Materials: A total of 100 pregnant women with microcytic hypochromic anaemia (iron deficiency anaemia) as determined by peripheral smear were included. The total dose will be determined using the formula. While women in Group B (n=50) received injections of iron sucrose, women in Group A (n=50) received injections of ferric carboxy maltose. Results: Most patients in Group A (46%) and in Group B (46%) had their pre-treatment Hb in range of 8-8.9 g/dl. Majority of patients in both groups had their pre-treatment serum ferritin in range of 10-19.9 mcg/l. At 2 weeks and three week post treatment, the rise in mean Hb level was more in Group A as compared to Group B. Statistically the rise was highly significant. Conclusion: From our study we concluded that injection Ferrous carboxy maltose appears to be safe and efficient for correction of iron deficiency anaemia in third trimester of pregnancy with lesser adverse effects and better patient compliance.
Abstract (English)
Background: Iron deficiency anaemia is the most common form of anaemia during pregnancy. It may have detrimental effects on the mother and growing foetus. There is need to study the effectiveness and safety of injection ferric carboxy maltose and injection iron sucrose in pregnant women havinganaemia. Aim: To carry out a comparative study of injection ferric carboxy maltose and injection iron sucrose for treatment of iron deficiency anaemia in pregnancy at Kamla Raja Hospital, Gwalior. Methods and Materials: A total of 100 pregnant women with microcytic hypochromic anaemia (iron deficiency anaemia) as determined by peripheral smear were included. The total dose will be determined using the formula. While women in Group B (n=50) received injections of iron sucrose, women in Group A (n=50) received injections of ferric carboxy maltose. Results: Most patients in Group A (46%) and in Group B (46%) had their pre-treatment Hb in range of 8-8.9 g/dl. Majority of patients in both groups had their pre-treatment serum ferritin in range of 10-19.9 mcg/l. At 2 weeks and three week post treatment, the rise in mean Hb level was more in Group A as compared to Group B. Statistically the rise was highly significant. Conclusion: From our study we concluded that injection Ferrous carboxy maltose appears to be safe and efficient for correction of iron deficiency anaemia in third trimester of pregnancy with lesser adverse effects and better patient compliance.
Files
IJPCR,Vol14,Issue11,Article62.pdf
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Additional details
Dates
- Accepted
-
2022-11-12
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/14/IJPCR,Vol14,Issue11,Article62.pdf
- Development Status
- Active
References
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