A Prospective Hospital Based Study to Assess the Correlation Between Glycemic Control, Lipid Profile and C-Reactive Protein in Adults with Type 2 Diabetes Mellitus
Authors/Creators
- 1. 2nd year PG, Department of Medicine, Nalanda Medical College & Hospital, Patna, Bihar, India
- 2. Assistant Professor, Department of Medicine, Nalanda Medical College & Hospital, Patna, Bihar, India
Description
Introduction: Onset of type 2 diabetes mellitus (T2DM) at early age heralds many years of disease and an increased risk that the full range of both microvascular and macrovascular complications will occur when affected individuals are still relatively young. Thus, further generations may be burdened with morbidity and mortality at the height of their productivity, potentially affecting workface, and healthcare systems of countries across the world. Methods: Total 50 patients with T2DM reporting to Nalanda Medical College & Hospital, Patna were included in the study, in whom CRP levels were estimated by using commercially available kits and correlated with HbA1C and other risk factors of coronary artery disease. Follow-up was done on 10 patients who were not on statin therapy with repeat HbA1C and CRP. Results: This study showed that both HbA1C and CRP levels had reduced significantly in follow-up patients after putting them on treatment (p<0.05). It was also found that lowers the HbA1C, lower was the CRP. A positive correlation was found between HbA1C and CRP (p<0.05). Conclusion: A positive correlation was found between serum CRP and HbA1C in the initial group and in the follow-up patients, showing that CRP levels lowers with better glycemic control and correlates with dyslipidemia profile.
Abstract (English)
Introduction: Onset of type 2 diabetes mellitus (T2DM) at early age heralds many years of disease and an increased risk that the full range of both microvascular and macrovascular complications will occur when affected individuals are still relatively young. Thus, further generations may be burdened with morbidity and mortality at the height of their productivity, potentially affecting workface, and healthcare systems of countries across the world. Methods: Total 50 patients with T2DM reporting to Nalanda Medical College & Hospital, Patna were included in the study, in whom CRP levels were estimated by using commercially available kits and correlated with HbA1C and other risk factors of coronary artery disease. Follow-up was done on 10 patients who were not on statin therapy with repeat HbA1C and CRP. Results: This study showed that both HbA1C and CRP levels had reduced significantly in follow-up patients after putting them on treatment (p<0.05). It was also found that lowers the HbA1C, lower was the CRP. A positive correlation was found between HbA1C and CRP (p<0.05). Conclusion: A positive correlation was found between serum CRP and HbA1C in the initial group and in the follow-up patients, showing that CRP levels lowers with better glycemic control and correlates with dyslipidemia profile.
Files
IJPCR,Vol14,Issue6,Article61.pdf
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Additional details
Dates
- Accepted
-
2022-05-05
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/14/IJPCR,Vol14,Issue6,Article61.pdf
- Development Status
- Active
References
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