A Prospective Study to Correlate Maternal and Perinatal Outcome with Ophthalmic Artery Doppler Velocimetry in Pre-Eclamptic and Normotensive Patients
- 1. MS (Obstetrics & Gynaecology), MBBS, LLB, Dean & Professor, Department of Obstetrics and Gynaecology Netaji Subhash Chandra Bose Medical College, Jabalpur (M. P.) MS (Obstetrics & Gynaecology)
- 2. Associate Professor, Department of Obstetrics and Gynaecology, Netaji Subhash Chandra Bose Medical College, Jabalpur (M. P.)
- 3. MBBS, Post Graduate Student, Department of Obstetrics and Gynaecology, Netaji Subhash Chandra Bose Medical College, Jabalpur (M. P.)
Description
Introduction: Hypertension is one of the most common clinical complications during pregnancy, complicating 6-10% of all pregnancies. Ophthalmic artery provides an accessible window for easy monitoring of maternal cardiovascular changes especially in pregnancy complicated hypertension cases. Aims and Objectives: To correlate maternal and perinatal outcome with the Ophthalmic Artery Doppler (OAD) parameters observed in the Pre-eclamptic subjects with those observed in Normotensive subjects. Material and Methods: A prospective case-control study was conducted in the Department of Obstetrics and Gynaecology, Netaji Subhash Chandra Bose Medical College, Jabalpur, in 126 pregnant subjects (63 Pre-eclamptic patients and 63 Normotensive pregnant controls) in their 2nd and 3rd trimester. They underwent serial OAD velocimetry between 20 weeks to term at three different points of time. OAD parameters, such as Pulsatility Index, Resistance Index, Peak Systolic Velocity, Peak Diastolic Velocity, End Diastolic Velocity and Peak Ratio were measured on transorbital triplex ultrasound scan with 10 MHz linear transducer. These parameters were correlated with maternal and perinatal outcomes. P < 0.05 was considered to be statistically significant. Results: Pulsatility Index and Resistance Index were significantly reduced and Peak Ratio was significantly higher in the Pre-eclamptic subjects than the Normotensive subjects. Maternal and perinatal complications were statistically significantly more frequent in subjects with OAD changes rather than those who were hypertensive without OAD changes or were normotensive. Conclusion: Ophthalmic Artery Doppler velocimetry, in conjunction with other parameters for monitoring maternal and perinatal wellbeing, can be a useful predictor of pregnancy outcome when used accurately and judiciously.
Abstract (English)
Introduction: Hypertension is one of the most common clinical complications during pregnancy, complicating 6-10% of all pregnancies. Ophthalmic artery provides an accessible window for easy monitoring of maternal cardiovascular changes especially in pregnancy complicated hypertension cases. Aims and Objectives: To correlate maternal and perinatal outcome with the Ophthalmic Artery Doppler (OAD) parameters observed in the Pre-eclamptic subjects with those observed in Normotensive subjects. Material and Methods: A prospective case-control study was conducted in the Department of Obstetrics and Gynaecology, Netaji Subhash Chandra Bose Medical College, Jabalpur, in 126 pregnant subjects (63 Pre-eclamptic patients and 63 Normotensive pregnant controls) in their 2nd and 3rd trimester. They underwent serial OAD velocimetry between 20 weeks to term at three different points of time. OAD parameters, such as Pulsatility Index, Resistance Index, Peak Systolic Velocity, Peak Diastolic Velocity, End Diastolic Velocity and Peak Ratio were measured on transorbital triplex ultrasound scan with 10 MHz linear transducer. These parameters were correlated with maternal and perinatal outcomes. P < 0.05 was considered to be statistically significant. Results: Pulsatility Index and Resistance Index were significantly reduced and Peak Ratio was significantly higher in the Pre-eclamptic subjects than the Normotensive subjects. Maternal and perinatal complications were statistically significantly more frequent in subjects with OAD changes rather than those who were hypertensive without OAD changes or were normotensive. Conclusion: Ophthalmic Artery Doppler velocimetry, in conjunction with other parameters for monitoring maternal and perinatal wellbeing, can be a useful predictor of pregnancy outcome when used accurately and judiciously.
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IJPCR,Vol16,Issue8,Article147.pdf
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Additional details
Dates
- Accepted
-
2024-07-25
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/16/IJPCR,Vol16,Issue8,Article147.pdf
- Development Status
- Active
References
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