Published 2016 | Version v1

Sequencing and molecular modeling identifies candidate members of Caliciviridae family in bats

Description

(Uploaded by Plazi for the Bat Literature Project) Emerging viral diseases represent an ongoing challenge for globalized world and bats constitute an immense, partially explored, reservoir of potentially zoonotic viruses. Caliciviruses are important human and animal pathogens and, as observed for human noroviruses, they may impact on human health on a global scale. By screening fecal samples of bats in Hungary, calicivirus RNA was identified in the samples of Myotis daubentonii and Eptesicus serotinus bats. In order to characterize more in detail the bat caliciviruses, large portions of the genome sequence of the viruses were determined. Phylogenetic analyses and molecular modeling identified firmly the two viruses as candidate members within the Caliciviridae family, with one calicivirus strain resembling members of the Sapovirus genus and the other bat calicivirus being more related to porcine caliciviruses of the proposed genus Valovirus. This data serves the effort for detecting reservoir hosts for potential emerging viruses and recognize important evolutionary relationships.

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Additional details

Identifiers

URL
hash://md5/0949484bf130051abd77a299e0c8987d
URN
urn:lsid:zotero.org:groups:5435545:items:2IHLCL5I
DOI
10.1016/j.meegid.2016.04.004

Biodiversity

Kingdom
Animalia
Phylum
Chordata
Class
Mammalia
Order
Chiroptera