A Retrospective Study on the Correlation between BMI and COPD in Middle Aged Males using Computerized Spirometry
Authors/Creators
- 1. Associate Professor, Department of Physiology, PSGIMS&R, Coimbatore -04
Description
Introduction: Obesity is a condition characterized with an increase in size and amount of fat cells in the body. Obesity is caused by imbalance of energy intake (“Diet”) and energy expenditure (“physical activity”). In the present world, there is a major epidemic of Obesity and many obese patients suffer with respiratory symptoms and disease. Obesity can affect the thorax, diaphragm and abdominal muscles, thereby resulting in altered respiratory functions. In this retrospective study, BMI was correlated with COPD (Chronic Obstructive Pulmonary Disease) and the variations in respiratory parameters were noted down. Objectives: (1) Primary objective: To assess the significance between BMI and COPD. (2) Secondary Objective: To propagate the results among the general public about the correlation between Obesity and COPD. Methodology: The pulmonary function test data were randomly selected. This is a retrospective study. The data was obtained from the procedure performed for the diagnosis of patient’s condition. About 60 spirometric values were used for the study (40 subjects with COPD / 20 subjects with normal PFT values). The criteria for COPD diagnosis was airflow limitation irreversible with bronchodilator or only partially reversible with bronchodilator. The best PFT indicator is low FEV1 / FVC ratio below 70% of predicted values. Result: The association between pulmonary function test and BMI was done. There is moderately positive correlation between FEV1 and BMI and similarly between FEV1/ FVC % and BMI. Pearson correlation coefficient analysis was done. P – Value <0.05 was considered to be statistically significant. Conclusion: The purpose of this paper is to determine if there is an association between obesity level and prevalence of COPD. The obesity epidemic poses a new challenge to health professionals caring for patients with chronic respiratory diseases. The impact of obesity on COPD has been much less studied. So there should be an increase in quantity and quality of studies on the association between BMI and COPD in the medical world.
Abstract (English)
Introduction: Obesity is a condition characterized with an increase in size and amount of fat cells in the body. Obesity is caused by imbalance of energy intake (“Diet”) and energy expenditure (“physical activity”). In the present world, there is a major epidemic of Obesity and many obese patients suffer with respiratory symptoms and disease. Obesity can affect the thorax, diaphragm and abdominal muscles, thereby resulting in altered respiratory functions. In this retrospective study, BMI was correlated with COPD (Chronic Obstructive Pulmonary Disease) and the variations in respiratory parameters were noted down. Objectives: (1) Primary objective: To assess the significance between BMI and COPD. (2) Secondary Objective: To propagate the results among the general public about the correlation between Obesity and COPD. Methodology: The pulmonary function test data were randomly selected. This is a retrospective study. The data was obtained from the procedure performed for the diagnosis of patient’s condition. About 60 spirometric values were used for the study (40 subjects with COPD / 20 subjects with normal PFT values). The criteria for COPD diagnosis was airflow limitation irreversible with bronchodilator or only partially reversible with bronchodilator. The best PFT indicator is low FEV1 / FVC ratio below 70% of predicted values. Result: The association between pulmonary function test and BMI was done. There is moderately positive correlation between FEV1 and BMI and similarly between FEV1/ FVC % and BMI. Pearson correlation coefficient analysis was done. P – Value <0.05 was considered to be statistically significant. Conclusion: The purpose of this paper is to determine if there is an association between obesity level and prevalence of COPD. The obesity epidemic poses a new challenge to health professionals caring for patients with chronic respiratory diseases. The impact of obesity on COPD has been much less studied. So there should be an increase in quantity and quality of studies on the association between BMI and COPD in the medical world.
Files
IJPCR,Vol16,Issue8,Article107.pdf
Files
(333.1 kB)
| Name | Size | Download all |
|---|---|---|
|
md5:c1a54817189c041df4e4bc7e173bc4c4
|
333.1 kB | Preview Download |
Additional details
Dates
- Accepted
-
2024-07-26
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/16/IJPCR,Vol16,Issue8,Article107.pdf
- Development Status
- Active
References
- 1. Banerjee J, Roy A, Singhamahapatra A, Dey PK, Ghosal A, Das A. Association of Body Mass index (BMI) with lung function parameters in non-asthmatics identified by spirometric protocols J Clin Diagn Res. 2014. Feb ;8 (2); 12-14. 2. Jones RL, Nzekulu MM. The effects of Body Mass Index on lung volumes Chest. 2006. Sep;130(3): 827-833. 3. Steier J, Lunt A, Hart N et al. Observational study of the effect of obesity on lung volumes. Thorax. 2014. August; 69(8):752-9. 4. Cheryl M Saloma, Gregory G King, Norbert Bevend. Physiology of obesity and effects on lung function. J Appl Physiology. 2010; 108: 206-11. 5. Garrow JS, Webster J. Quetelet's index as a measure of fatness. Int J obes 1985;9(2): 147- 153 6. Rasslen Z, Junior RS, Stirbulor R et al. Evaluation of Pulmonary Function in Class I and Class II obesity 2004. J Clin Diagn Res. 2014 Feb 3. 7. Al Ghobain M. The effect of obesity on spirometry tests among healthy non-smoking adults. Pulmnary Medicine. 2012; 12:10. 8. Biring MS, Lewis MI, Lin JT, et al. Pulmonary physiological changes of morbid obesity. Am J Med Sci. 1999 November; 318 (5):293-7. 9. Yang L, Zhou M, Smith M, Peto R, Wang J et al. Body mass index and COPD – related mortality. A nationally representative prospective study of 2, 20, 000 men in China. Int J Epidemiol. 2010; 39:1027 -1036. 10. Yilan Sun, Stephen Milne, Jen Erh Jaw, Chen xi Yang et al., BMI is associated with FEV1 decline in COPD: a meta-analysis of clinical trials. Respiratory Research Volume 20, Article Number 236. 2019. 11. Harik – Khan RI, Flag JL Wise RA. Body Mass Index and the risk of COPD. Chest. 2002; 121(2): 370-6 12. F. Franssen, D. D' Donnell, G. Goosens, E. Blaak, and A. Schols. "obesity and the lung: obesity and COPD" Thorax, 2008; 63(12): 1110-1117.