Published August 22, 2024 | Version v1
Dataset Open

Analysis of single-cell CRISPR perturbations indicates that enhancers predominantly act multiplicatively

Authors/Creators

  • 1. ROR icon University of California, San Diego
  • 2. ROR icon Salk Institute for Biological Studies

Description

This repository contains simulated data generated with GLiMMIRS-sim that was analyzed and presented in Zhou & Guyuvayurappan et al, as well as data pertaining to the NMU RT-qPCR experiment described in the manuscript. 

 

  • sim_base_data.tar.gz: directory containing simulated data for baseline model 

  • sim_data_interactions_pos.tar.gz: directory containing simulated data for interactions model with positive interaction effects 

  • sim_data_interactions_neg.tar.gz: directory containing simulated data for interactions model with negative interaction effects 

  • NMU.xlsx: spreadsheet containing data from the NMU RT-qPCR experiment 

Files

Files (50.3 GB)

Name Size Download all
md5:1298e0ee8e8174da94b0cfb0bc263a5f
928.7 kB Download
md5:ce1ad0972b2245688a2c092b3b5fddb2
9.5 GB Download
md5:c0a67f0c0d7a1c9297929599d5a31bc6
20.5 GB Download
md5:4830eda15af6cd0eb53a2f23c94a70ef
20.4 GB Download

Additional details

Related works

Is described by
Publication: 10.1101/2023.04.26.538501 (DOI)

Funding

National Institutes of Health
Ruth L. Kirschstein Predoctoral Individual National Research Service Award F31DA056226
National Institutes of Health
Maximizing Investigators' Research Award (MIRA) (R35) R35HG011315
Fulbright Association

Software

Repository URL
https://github.com/mcvickerlab/GLiMMIRS
Development Status
Active