Published January 23, 2026
| Version v2
Dataset
Open
TRcompDB v2.0, a global reference of human tandem repeat composition and mutation rate from long-read assemblies
Authors/Creators
-
1.
University of Southern California
Description
The following motif catalogs are provided. Including
- the vamos genomic catalog expanded by TRExplore v1.0 (4,422,661 loci) for GRCh38
- the vamos genomic catalog for CHM13 (1,175,989 loci)
- the vamos genomic catalog expanded by TRExplore v1.0 (4,155,246 loci) for CHM13
- the curated functional catalog for GRCh38 (72 loci)
All motif catalogs are generated under the v3.0 infrastructure of the catalog construction pipeline. “oriMotifs” stands for the full motif set before efficient motif selection. “effMotifs-0.1” stands for the efficient motifs selected under q=0.1.
TR annotations are provided as combined vcf for 416 publicly available diploid long-read assemblies.
Locus-specific ANOVAs by allelic length or compositions are provided in "anova.annoLen.tsv.gz" and "anova.ed2Major.tsv.gz".
Estimated locus-specific mutation rates for GRCh38 are provided in a master table with locus features (mutRate_GRCh38_masterFile.tsv.gz). Columns are explained in the txt file (mutRate_GRCh38_masterFile.txt).
Files
mutRate_GRCh38_masterFile.txt
Files
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Additional details
Funding
- National Human Genome Research Institute
- Computational methods for detecting and genotyping human genetic variation using single-molecule sequencing and high-throughput short read data R01HG010756