Single Cell RNA Transcriptomics of Mantle Cell Lymphoma Reveals the Presence of Treatment-Resistant Subclones at the Time of Diagnosis - Supplementary Data Tables
Authors/Creators
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Kazantsev, Dmitry
(Researcher)1
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Klánová, Magdalena
(Contact person)1, 2
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Kolář, Michal
(Researcher)3
- Ivánek, Robert (Researcher)4
- Geier, Florian (Researcher)4
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Roux, Julien
(Researcher)4
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Zikmund, Tomáš
(Researcher)1
- Kriegová, Eva (Researcher)5
- Maňáková, Jiřina (Researcher)5
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Trněný, Marek
(Supervisor)2
- et al. Show all 11 authors
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Kazantsev, Dmitry
(Researcher)1
-
Klánová, Magdalena
(Contact person)1, 2
-
Kolář, Michal
(Researcher)3
- Ivánek, Robert (Researcher)4
- Geier, Florian (Researcher)4
-
Roux, Julien
(Researcher)4
-
Zikmund, Tomáš
(Researcher)1
- Kriegová, Eva (Researcher)5
- Maňáková, Jiřina (Researcher)5
-
Trněný, Marek
(Supervisor)2
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Klener, Pavel
(Supervisor)1, 2
- 1. Institute of Pathological Physiology, First Faculty of Medicine, Charles University, Prague, Czech Republic
- 2. First Department of Medicine-Department of Hematology, Charles University General Hospital in Prague, Czech Republic
- 3. Institute of Molecular Genetics, Czech Academy of Sciences, Prague, Czech Republic
- 4. Department of Biomedicine, Bioinformatics Core Facility, University Hospital Basel, Switzerland
- 5. Department of Immunology, Palacký University Olomouc and University Hospital Olomouc, Olomouc, Czech Republic
Description
Supplementary Table 4. Results of optical genomic mapping for patient P009. The table lists genomic aberrations shared for diagnosis and relapse and those exclusive at both timepoints.
Supplementary Table 5. Lists of differentially expressed genes in DGs subclones compared to DGex for each patient. A result of pseudobulk analysis with DECENT R package.
Supplementary Table 6. Gene set analysis results of differentially expressed genes in DGs subclones compared to DGex using Reactome pathways.
Supplementary Table 7. Copy number variant segments predicted using whole exome sequencing data. Results of copy segments analysis and copy number calling using CNVkit.
Supplementary Table 8. Short nucleotide variants detected in whole exome sequencing data of P069 at diagnosis in PBMC and at relapse in bone marrow and intestine samples. Results of Mutect2 variant calling algorithm.