ADVANCES IN MEDICAL MANAGEMENT OF DIABETES

Introduction: Diabetes mellitus (DM) is a growing global epidemic that is causing a significant socioeconomic burden on nations. Since the traditional methods of treatment have significant side effects and have not addressed the disease's underlying causes, new strategies for managing diabetes mellitus are emerging quickly. Therefore, in order to create a clinical management plan that is strong, effective, and safe, the issues with each of these techniques must be resolved. The best possible metabolic management of blood pressure, glucose, and body weight is necessary, and improving diet, increasing physical activity, and reducing body weight all require the right information and assistance.

Aim of the study: This narrative review discusses various treatment plans, developments in the management of diabetes mellitus, and related challenges.

Methodology: The review is comprehensive research of PUBMED since year1995 to 2024.

Conclusion: Significant advancements in the treatment of diabetes mellitus have shown encouraging outcomes through the application of several therapeutic approaches, such as medical nutrition therapy, gene therapy, stem cell, nanotechnology, and lifestyle change. Nevertheless, there have been many difficulties in applying these techniques, such as optimizing them to guarantee the best possible blood pressure, cholesterol, and glucose regulation to reduce complications; enhancing patient adherence to pharmacological and lifestyle interventions; safety; ethical concerns; and developing an efficient delivery system, among other difficulties.

Keywords – Diabetes mellitus, gene therapy, advance monitoring and drug delivery