Published June 30, 2024 | Version https://impactfactor.org/PDF/IJPCR/16/IJPCR,Vol16,Issue6,Article347.pdf
Journal article Open

Analysis of Tramadol and Dexamethasone as an Adjuvant to Bupivacaine

Authors/Creators

  • 1. Assistant Professor, Department of Anaesthesia. Vedantaa Institute of Medical Sciences, Dahanu Palghar
  • 2. M.D. (Anaesthesia), FCCCM (Critical Care Medicine), CIH (Industrial Health), Assistant Professor, Vedantaa Institute of Medical Sciences & Research Centre, Palghar (Maharashtra)

Description

Introduction: It is necessary to reduce unbearable pain after surgery. Bupivacaine was used as an anaesthetic but recently scientists are cultivating the use of Tramadol and Dexamethasome with Bupivacaine as an effective adjuvant to increase the potentiality of Bupivacaine. Tramadol has been used for the reduction of the unbearable pain after surgery while dexamethasome has been used for the cure of the inflammation caused after operative measure. The study provides  different other ways for reducing pain and the patients tendency to request for analgesics. Aims and Objective: To compare the post-operative analgesic efficacy of tramadol and dexamethasone as an adjuvant to bupivacaine. Method: The observational study was carried out in India among 120 randomly selected patients into 3 groups, considering different inclusion and exclusion criteria with proper written consent of the patients. 20-30 age group patients should be allowed with orthopedic surgery in the upper limb. Different tests like ANOVA, paired t test, chi square tests etc were carried out for maintaining statistical significance. Result: Group I (tramadol) had a sensory response mean of 10.85 (SD 3.05) and motor response mean of 21.83 (SD 4.55). Group II (Dexamethasone) had a sensory response mean of 10 (SD 2.12) and motor response mean of 15.14 (SD 4.25). Group III showed sensory and motor response means of 21.25 (SD 6.25) and 28.19 (SD 4.45), respectively. Group II’s sensory block mean duration was 420.65 minutes (p=0.0355), and motor block mean was 356 minutes (p=0.0498). Analgesic dose timing in Group II averaged 655.36 minutes (p=0.0335). Conclusion: Dexamethasone significantly better sensory and motor responses, as well as more favorable durations for sensory and motor blocks.

 

 

 

Abstract (English)

Introduction: It is necessary to reduce unbearable pain after surgery. Bupivacaine was used as an anaesthetic but recently scientists are cultivating the use of Tramadol and Dexamethasome with Bupivacaine as an effective adjuvant to increase the potentiality of Bupivacaine. Tramadol has been used for the reduction of the unbearable pain after surgery while dexamethasome has been used for the cure of the inflammation caused after operative measure. The study provides  different other ways for reducing pain and the patients tendency to request for analgesics. Aims and Objective: To compare the post-operative analgesic efficacy of tramadol and dexamethasone as an adjuvant to bupivacaine. Method: The observational study was carried out in India among 120 randomly selected patients into 3 groups, considering different inclusion and exclusion criteria with proper written consent of the patients. 20-30 age group patients should be allowed with orthopedic surgery in the upper limb. Different tests like ANOVA, paired t test, chi square tests etc were carried out for maintaining statistical significance. Result: Group I (tramadol) had a sensory response mean of 10.85 (SD 3.05) and motor response mean of 21.83 (SD 4.55). Group II (Dexamethasone) had a sensory response mean of 10 (SD 2.12) and motor response mean of 15.14 (SD 4.25). Group III showed sensory and motor response means of 21.25 (SD 6.25) and 28.19 (SD 4.45), respectively. Group II’s sensory block mean duration was 420.65 minutes (p=0.0355), and motor block mean was 356 minutes (p=0.0498). Analgesic dose timing in Group II averaged 655.36 minutes (p=0.0335). Conclusion: Dexamethasone significantly better sensory and motor responses, as well as more favorable durations for sensory and motor blocks.

 

 

 

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Dates

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2024-06-25

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