FORMULATION AND EVALUATION OF ELIXIR OF GYMNEMA SYLVESTRE BY USING LEAF EXTRACT

In the present research work, the main objective is to formulate and evaluate Elixir of Gymnema Sylvestre by using Leaf extract. There are lots of chemical agents available to control and to treat diabetic patients, but total recovery from diabetes has not been reported up to this date. Alternative to these synthetic agents, many herbal plants with hypoglycemic properties are known from across the world. Gymnema Sylvestre is an herb native to the tropical forests of southern and central India and Sri Lanka. The medicinal part of the plant is the leaf, which reduces or eliminates the ability to sweetness tastes. Gymnema sylvestre leaves are known for several medicinal uses such as antidiabetic, hypolipidemic, stomachic, diuretic, refrigerant, astringent and tonic, the major bioactive constituents of gymnema sylvestre are a group of triterpenoid glycosides known as gymnemic acids with gymnemagenin as common aglycone. Which is responsible for its tremendous activity specially its blood glucose lowering capacity. In this studies we have shown that the extract of gymnema sylvestre is useful in controlling blood sugar to treat type II diabetes (NIDDM) when gymnema leaf extract is administered to a diabetic patient it stimulate the pancreas to increase release of insulin. The elixirs were prepared by using Sodium Saccharin, Glycerin and Alcohol etc. The elixirs were evaluated for FTIR, Viscosity, PH, Refractive Index, Alcohol Content and Assay. In this preparation of the elixir is going to prepare by the simple solution method. It is a clear, sweetened, hydroalcoholic liquid intended for oral use. Keywords: Elixirs, Gymnema sylvestre, Sodium Saccharin, Diabetes, Herbal, Insulin.