A Study in the Occurrence of Thyroid Dysfunction among PatientsPresenting with Polymorphic Light Eruption (PLE)
Authors/Creators
- 1. Postgraduate, Department of Dermatology, Venereology and Leprology, Trichy SRM Medical College Hospital and Research Centre, Tiruchirappalli, Tamil Nadu, India
- 2. Professor and Head of the Department of Dermatology, Venereology and Leprology, Trichy SRM Medical College Hospital and Research Centre, Tiruchirappalli, Tamil Nadu, India
- 3. Associate Professor, Department of Dermatology, Venereology and Leprology, Trichy SRM Medical College Hospital and Research Centre, Tiruchirappalli, Tamil Nadu, India
Description
Background: Polymorphic light eruption (PLE) is a skin condition caused by exposure to UV radiation, and its development is often associated with auto-immune processes. Thyroid dysfunction has been observed in people with sunlight- induced skin conditions such as melasma and polymorphic light eruption (PLE). Aim: (1) To assess the levels of TSH in patients who have polymorphic mild eruption. (2) To establish a relationship between autoimmune thyroiditis and polymorphic light eruptions by estimating anti-TPO antibodies. Methods: The study comprised of 40 cases of PLE who attended our skin outpatient department. The clinical characteristics were documented, Thyroid-stimulating hormone (TSH), triiodothyronine (T3), tetraiodothyronine (T4) and anti-Tpo antibody levels were measured. Results: Mean (SD) age of the participants was 39.9 (14.8) years. 18 (45%) were male and 22 (55%) were female. Mean (SD) TSH levels were 3.15 (2.52). Mean (SD) anti TPO antibodies was 49.16 (107.6). 8 cases (20%) had increased TSH and 9 (22.5%) cases had increased anti TPO antibodies. Conclusion: Patients with PLE should undergo evaluation to determine if they have thyroid disorder, so that proper treatment can be given instead of only treating the discernible.
Abstract (English)
Background: Polymorphic light eruption (PLE) is a skin condition caused by exposure to UV radiation, and its development is often associated with auto-immune processes. Thyroid dysfunction has been observed in people with sunlight- induced skin conditions such as melasma and polymorphic light eruption (PLE). Aim: (1) To assess the levels of TSH in patients who have polymorphic mild eruption. (2) To establish a relationship between autoimmune thyroiditis and polymorphic light eruptions by estimating anti-TPO antibodies. Methods: The study comprised of 40 cases of PLE who attended our skin outpatient department. The clinical characteristics were documented, Thyroid-stimulating hormone (TSH), triiodothyronine (T3), tetraiodothyronine (T4) and anti-Tpo antibody levels were measured. Results: Mean (SD) age of the participants was 39.9 (14.8) years. 18 (45%) were male and 22 (55%) were female. Mean (SD) TSH levels were 3.15 (2.52). Mean (SD) anti TPO antibodies was 49.16 (107.6). 8 cases (20%) had increased TSH and 9 (22.5%) cases had increased anti TPO antibodies. Conclusion: Patients with PLE should undergo evaluation to determine if they have thyroid disorder, so that proper treatment can be given instead of only treating the discernible.
Files
IJPCR,Vol16,Issue7,Article114.pdf
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Additional details
Dates
- Accepted
-
2024-07-11
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/16/IJPCR,Vol16,Issue7,Article114.pdf
- Development Status
- Active
References
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