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Published April 13, 2015 | Version 3.3.3 (Gaia)
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SimThyr

Authors/Creators

  • 1. Bergmannsheil University Hospitals, Ruhr University of Bochum

Contributors

  • 1. Bergmannsheil University Hospitals, Ruhr University of Bochum
  • 2. Klinikum Luedenscheid
  • 3. North Lakes Clinical

Description

SimThyr is a numeric simulator of pituitary-thyroid feedback control (aka thyrotropic feedback control, hypothalamus-pituitary-thyroid axis or thyroid homeostasis).

Files

Kubota_et_al._2010_v1.1.zip

Files (14.6 MB)

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Additional details

Is cited by
23365787 (PMID)
PMC3544290 (pmcid)
10.1136/jclinpath-2012-201213 (DOI)
23423518 (PMID)
10.1530/EJE-12-0819 (DOI)
23184912 (PMID)
25750078 (PMID)
10.1055/s-0034-1398616 (DOI)
Is supplement to
978-3-89722-850-4 (ISBN)
10.1155/2012/351864 (DOI)

References

  • J. W. DIETRICH, A. TESCHE, C. R. PICKARDT & U. MITZDORF (2004) THYROTROPIC FEEDBACK CONTROL: EVIDENCE FOR AN ADDITIONAL ULTRASHORT FEEDBACK LOOP FROM FRACTAL ANALYSIS, Cybernetics and Systems, 35:4, 315-331, DOI: 10.1080/01969720490443354
  • Johannes W. Dietrich, Gabi Landgrafe, and Elisavet H. Fotiadou, "TSH and Thyrotropic Agonists: Key Actors in Thyroid Homeostasis," Journal of Thyroid Research, vol. 2012, Article ID 351864, 29 pages, 2012. https://doi.org/10.1155/2012/351864.
  • Midgley JEM, Hoermann R, Larisch R, Dietrich JW. Physiological states and functional relation between thyrotropin and free thyroxine in thyroid health and disease: in vivo and in silico data suggest a hierarchical model. Journal of Clinical Pathology 2013;66:335-342.
  • Hoermann R, Midgley JE, Larisch R, Dietrich JW. Is pituitary TSH an adequate measure of thyroid hormone-controlled homoeostasis during thyroxine treatment? Eur J Endocrinol. 2013 Jan 17;168(2):271-80. doi: 10.1530/EJE-12-0819. PMID 23184912.
  • Hoermann R, Midgley JE, Larisch R, Dietrich JW. Integration of Peripheral and Glandular Regulation of Triiodothyronine Production by Thyrotropin in Untreated and Thyroxine-Treated Subjects. Horm Metab Res. 2015 Aug;47(9):674-80. doi: 10.1055/s-0034-1398616. PMID 25750078.