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Published January 26, 2013 | Version 3.2.2 (Meridian)
Software Open

SimThyr

Authors/Creators

  • 1. Bergmannsheil University Hospitals, Ruhr University of Bochum
  • 1. Bergmannsheil University Hospitals, Ruhr University of Bochum
  • 2. Klinikum Luedenscheid
  • 3. North Lakes Clinical

Description

SimThyr is a numeric simulator of pituitary-thyroid feedback control (aka thyrotropic feedback control, hypothalamus-pituitary-thyroid axis or thyroid homeostasis).

Files

simthyr_3_2_2-setup.zip

Files (25.3 MB)

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Additional details

References

  • J. W. DIETRICH, A. TESCHE, C. R. PICKARDT & U. MITZDORF (2004) THYROTROPIC FEEDBACK CONTROL: EVIDENCE FOR AN ADDITIONAL ULTRASHORT FEEDBACK LOOP FROM FRACTAL ANALYSIS, Cybernetics and Systems, 35:4, 315-331, DOI: 10.1080/01969720490443354
  • Johannes W. Dietrich, Gabi Landgrafe, and Elisavet H. Fotiadou, "TSH and Thyrotropic Agonists: Key Actors in Thyroid Homeostasis," Journal of Thyroid Research, vol. 2012, Article ID 351864, 29 pages, 2012. https://doi.org/10.1155/2012/351864.
  • Midgley JEM, Hoermann R, Larisch R, Dietrich JW. Physiological states and functional relation between thyrotropin and free thyroxine in thyroid health and disease: in vivo and in silico data suggest a hierarchical model. Journal of Clinical Pathology 2013;66:335-342.
  • Hoermann R, Midgley JE, Larisch R, Dietrich JW. Is pituitary TSH an adequate measure of thyroid hormone-controlled homoeostasis during thyroxine treatment? Eur J Endocrinol. 2013 Jan 17;168(2):271-80. doi: 10.1530/EJE-12-0819. PMID 23184912.