Antibodies to FimH in Anti-neutrophil cytoplasmic antibody - associated vasculitis
- Miriam Jane Ball1
- Andrea Peschel1
- Tjerk Feenstra1
- Guerkan Sengoelge2
- Barbara Thompson3
- Ricarda Brandes1
- Andre Oszwald1
- F Mustafa Awad-El-Kariem4
- Heinz Burgmann5
- Dieter Mitteregger6
- Mariane S Thøgersen7
- Rolf K Sommer7
- D James Haddon8
- Thomas Perkmann9
- Thomas Wrba10
- Frank M Aarestrup7
- Paul J Utz8
- Andrew J Rees1
- Renate Kain1
- 1. Institute of Pathology, Medical University Vienna, Austria
- 2. Department of Medicine III, Division Nephrology and Dialysis, Medical University Vienna, Austria
- 3. Department of Nephrology, East and North Hertfordshire NHS Trust, UK
- 4. Department of Microbiology, East and North Hertfordshire NHS Trust, UK
- 5. Department of Medicine I, Division Infectious diseases and Tropical medicine, Medical University Vienna, Austria
- 6. Department of Clinical Microbiology, Medical University Vienna, Austria
- 7. National Food Institute, Technical University of Denmark, DK
- 8. Department of Medicine, Division of Immunology & Rheumatology, Stanford University School of Medicine, Stanford, CA, USA
- 9. Department of Laboratory Medicine, Medical University Vienna, Austria
- 10. IT systems and communication, Medical University Vienna, Austria
Description
Peptide microarray containing 4216 unique peptides from 88 different microorganisms represented by validated B-cell epitopes selected from the Immune Epitope Database (http://www.iedb.org). A total of 1509 bacterial, 2311 viral, 12 fungal and 384 protozoal epitopes were printed on the arrays. This array was probed with serum from 8 patients with ANCA-associated vasculitis collected at presentation with the disease as well as in remission and analysed for binding by IgM and IgG.
Notes
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