A Retrospective Study Determining the Clinical Relationship between Migraine and Mood Disorders
Authors/Creators
- 1. Senior Resident, Department of Psychiatry, IHBAS, Delhi, India
- 2. Senior Resident, Department of Psychiatry, MGMCH, Jaipur, Rajasthan, India
- 3. Professor and HOD, Department of Psychiatry, MGMCH, Jaipur, Rajasthan, India
Description
Abstract
Aim: To investigate the clinical relationship between migraine and mood disorders.
Material and Methods: This retrospective study was carried out in the Department of Psychiatry, IHBAS, Delhi,
India for one year. Each patient was evaluated in detail with a questionnaire with details regarding the duration of
headache, frequency and duration of each episode, site, quality and severity of pain, auras, migraine
accompaniments such as photo or phonophobia, nausea, vomiting as well as triggers. To assess disability,
Migraine Disability Assessment Questionnaire (MIDAS) was applied to all patients. A score of 6 or more is taken
as positive with cut offs for mild, moderate, and severe disability. The presence of concurrent anxiety and mood
disorders was assessed by the Hospital Anxiety and Depression Scale (HADS).
Results: A total of 200 patients were studied during the study. The sample consisted mostly (n = 160, 80%) of
middle age (20-50 years) Individuals with mean (standard deviation [SD]) of age of 35.12 (8.58) years. It was a
female predominant sample (n = 138, 69%). As per HADS score, among the 22 patients (11%) suffering from
depressive symptoms, 50% had borderline abnormal score and 16% (n = 32) had abnormal score whereas among
the 27 persons (54%) suffering from anxiety 18% had borderline score and 50% had abnormal score. Mean HADS
score (SD) of depression was 11.24 (3.04) while that of anxiety was 13.81 (2.71). Median of duration of headache
was 6 years with SD of 6.5 years. Here, duration of disease was not normally distributed, so nonparametric
statistics were applied. Though female individuals had more duration of illness (mean rank: 69.87), it was not
significantly different (P = 0.04) from males (mean rank: 58.47). Middle-aged individuals suffered more duration
of illness than other age groups (P < 0.04).
Conclusion: We concluded that the mood disorders are comorbid with migraine at a rate comparable to or less
than that described in many studies in international literature and the occurrence of comorbid mood disorders
significantly contributes to migraine associated disability.
Abstract (English)
Abstract
Aim: To investigate the clinical relationship between migraine and mood disorders.
Material and Methods: This retrospective study was carried out in the Department of Psychiatry, IHBAS, Delhi,
India for one year. Each patient was evaluated in detail with a questionnaire with details regarding the duration of
headache, frequency and duration of each episode, site, quality and severity of pain, auras, migraine
accompaniments such as photo or phonophobia, nausea, vomiting as well as triggers. To assess disability,
Migraine Disability Assessment Questionnaire (MIDAS) was applied to all patients. A score of 6 or more is taken
as positive with cut offs for mild, moderate, and severe disability. The presence of concurrent anxiety and mood
disorders was assessed by the Hospital Anxiety and Depression Scale (HADS).
Results: A total of 200 patients were studied during the study. The sample consisted mostly (n = 160, 80%) of
middle age (20-50 years) Individuals with mean (standard deviation [SD]) of age of 35.12 (8.58) years. It was a
female predominant sample (n = 138, 69%). As per HADS score, among the 22 patients (11%) suffering from
depressive symptoms, 50% had borderline abnormal score and 16% (n = 32) had abnormal score whereas among
the 27 persons (54%) suffering from anxiety 18% had borderline score and 50% had abnormal score. Mean HADS
score (SD) of depression was 11.24 (3.04) while that of anxiety was 13.81 (2.71). Median of duration of headache
was 6 years with SD of 6.5 years. Here, duration of disease was not normally distributed, so nonparametric
statistics were applied. Though female individuals had more duration of illness (mean rank: 69.87), it was not
significantly different (P = 0.04) from males (mean rank: 58.47). Middle-aged individuals suffered more duration
of illness than other age groups (P < 0.04).
Conclusion: We concluded that the mood disorders are comorbid with migraine at a rate comparable to or less
than that described in many studies in international literature and the occurrence of comorbid mood disorders
significantly contributes to migraine associated disability.
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Additional details
Dates
- Accepted
-
2024-01-22