Prospective Study of Lipid Profile in Oral Sub-Mucosal Fibrosis in Different Age Groups of Jharkhand Population
Authors/Creators
- 1. Assistant Professor, Department of ENT, Mahatma Gandhi Memorial Medical College, Jamshedpur - 831020
- 2. Junior Resident, Department of ENT, Mahatma Gandhi Memorial Medical College, Jamshedpur - 831020
- 3. Senior Resident, Department of ENT, Mahatma Gandhi Memorial Medical College, Jamshedpur - 831020
Description
Background: Oral Submucosal fibrosis (OSMF) is a quite common disease in adults who chew areca and to-bacco. Hence, severity or degrees of fibrosis have to be ruled out because it is a pre-cancerous symptom. Methods: 90 (ninety) adult OSMF patients were studied. The lipid profile was carried out in all patients and compared with the normal (controlled) group. Fasting 3 Ml venous blood sample was collected under aseptic precautions in plane vial from every patient, and the lipid profile was studied. Results: TC in OSMF was 134.3 (±8.6), 187.2 (±9.6) in the controlled group, and p<0.001. HDL profile was 28.2 (±4.8) in OSMF, 37.3 (±2.4) in the controlled group, and p<0.001. LDL level was 96.4 (± 4.4) in the OSMF group, 85.4 (± 16.4) in the controlled group, and 5.5 p<0.001. VLDL level was 16.8 (± 2.4) in OSMF, 39.4 (± 7.1) in controlled and p<0.001. TG level was 75.4 (± 10.2) in OSMF patients, 118.2 (± 18.4) in the controlled group, and p<0.001. Conclusion: The variations in parameters of lipid profile and erythrocyte level had a poor prognosis in OSMF patients. ENT surgeons have to take preventive measures to reduce morbidity and mortality in such patients.
Abstract (English)
Background: Oral Submucosal fibrosis (OSMF) is a quite common disease in adults who chew areca and to-bacco. Hence, severity or degrees of fibrosis have to be ruled out because it is a pre-cancerous symptom. Methods: 90 (ninety) adult OSMF patients were studied. The lipid profile was carried out in all patients and compared with the normal (controlled) group. Fasting 3 Ml venous blood sample was collected under aseptic precautions in plane vial from every patient, and the lipid profile was studied. Results: TC in OSMF was 134.3 (±8.6), 187.2 (±9.6) in the controlled group, and p<0.001. HDL profile was 28.2 (±4.8) in OSMF, 37.3 (±2.4) in the controlled group, and p<0.001. LDL level was 96.4 (± 4.4) in the OSMF group, 85.4 (± 16.4) in the controlled group, and 5.5 p<0.001. VLDL level was 16.8 (± 2.4) in OSMF, 39.4 (± 7.1) in controlled and p<0.001. TG level was 75.4 (± 10.2) in OSMF patients, 118.2 (± 18.4) in the controlled group, and p<0.001. Conclusion: The variations in parameters of lipid profile and erythrocyte level had a poor prognosis in OSMF patients. ENT surgeons have to take preventive measures to reduce morbidity and mortality in such patients.
Files
IJPCR,Vol16,Issue6,Article387.pdf
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Additional details
Dates
- Accepted
-
2024-05-26
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/16/IJPCR,Vol16,Issue6,Article387.pdf
- Development Status
- Active
References
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