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Published September 4, 2024 | Version v3.0.1

Muszeb/ENQUIRE: v3.0.1

Authors/Creators

  • 1. FAU Erlangen-Nuernberg, Uniklinikum Erlangen

Description

We implemented new features after a first revision round of the manuscript:

  1. We now distribute ENQUIRE also as a Docker Image, see here for more details.
  2. We implemented e-searching and e-fetching of "Other Term" (OT) PubMed fields for tokenization and normalization of gene mentions.
  3. We now also report PMIDs supporting significant co-occurrences in all node and edge tables (...Complete..., ...MeSH..., and ...Gene...). Additionally, node and edge tables of significant gene-gene co-occurrences (...Gene...) list Reactome Pathways and Reactions in which a gene-gene relation has been previously annotated.
  4. We implemented over-representation analysis of ENQUIRE-derived gene sets against known Reactome pathways in the context-aware gene set reconstruction script.
  5. We allow the users to extract the STRING reference network with node weights based on the ENQUIRE-reconstructed gene co-occurrence network in the context-aware pathway enrichment analysis script.

Full Changelog: https://github.com/Muszeb/ENQUIRE/compare/v2.0.0...v3.0.0

Files

Muszeb/ENQUIRE-v2.0.0.zip

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Additional details

Related works

Is supplement to
Software: https://github.com/Muszeb/ENQUIRE/tree/v3.0.1 (URL)