Published April 30, 2023 | Version https://impactfactor.org/PDF/IJPCR/15/IJPCR,Vol15,Issue4,Article114.pdf

Assessment of Right Heart Function and Dimensions following Device Closure of Atrial Septal Defect in Tertiary Medical Centre

  • 1. Assistant Professor, Department of Cardiology, LPS Institute of Cardiology, Kanpur, Uttar Pradesh
  • 2. Assistant Professor, Department of Cardiology, NMCH, Jamuhar, Sasaram, Bihar
  • 3. Assistant Professor, Department of Cardiology, PGICH, Noida, Uttar Pradesh

Description

Introduction: ASD closure causes electrical and mechanical reverse remodelling after shunt closure. There haven’t been many studies to determine whether surgical closure or device closure is better for regressing right heart volumes. In comparison to secundum ASD closure, transcatheter ASD closure has shown to be more affordable while eliminating the common risks of surgical closure, such as cardiac trauma and wound problems. Aim and Objective: To assess right heart function, right atrial and right ventricular dimensions pre and post transcatheter closure of atrial septal defect (ASD). Materials and Methods: From August 2021 to December 2022, 50 research participants participated in this descriptive longitudinal study at the LPS Institute of Cardiology in Kanpur, Uttar Pradesh. All ostium secundum ASD patients who were referred for closure were examined. Patients of both sexes are chosen for the investigation. For each patient, pertinent history, a clinical examination, pulse oximetry, a chest X-ray, and an ECG were performed. Each patient had a thorough transthoracic and transoesophageal echocardiogram performed. Results: At immediate post-closure, one week, and three months after closure, the mean RV longitudinal measurement was 6.31 cm, 6.07 cm, and 5.96 cm, respectively. F=359.324, P < 0.001, indicates that there is a significant difference between the 4 occurrences. Further numerous comparisons of the occasions reveal that every pair differs considerably. The mean MPI was 4.173, however, it fell to 3.93, 3.592, and 3.199 at the immediate, 1-week, and 3-month post-closure times. Further numerous comparisons of the occasions reveal that every pair differs considerably. F=444.425, P< 0.001 indicates that there is a significant difference between the 4 occurrences. Conclusions: Comparable positive effects are shown on hemodynamics, right heart dimensions, and functional capacity. Immediately upon device closure, the highest favourable effects on right cardiac functions, remodelling, of heart functions and the advantage is still there three months later.

 

 

 

Abstract (English)

Introduction: ASD closure causes electrical and mechanical reverse remodelling after shunt closure. There haven’t been many studies to determine whether surgical closure or device closure is better for regressing right heart volumes. In comparison to secundum ASD closure, transcatheter ASD closure has shown to be more affordable while eliminating the common risks of surgical closure, such as cardiac trauma and wound problems. Aim and Objective: To assess right heart function, right atrial and right ventricular dimensions pre and post transcatheter closure of atrial septal defect (ASD). Materials and Methods: From August 2021 to December 2022, 50 research participants participated in this descriptive longitudinal study at the LPS Institute of Cardiology in Kanpur, Uttar Pradesh. All ostium secundum ASD patients who were referred for closure were examined. Patients of both sexes are chosen for the investigation. For each patient, pertinent history, a clinical examination, pulse oximetry, a chest X-ray, and an ECG were performed. Each patient had a thorough transthoracic and transoesophageal echocardiogram performed. Results: At immediate post-closure, one week, and three months after closure, the mean RV longitudinal measurement was 6.31 cm, 6.07 cm, and 5.96 cm, respectively. F=359.324, P < 0.001, indicates that there is a significant difference between the 4 occurrences. Further numerous comparisons of the occasions reveal that every pair differs considerably. The mean MPI was 4.173, however, it fell to 3.93, 3.592, and 3.199 at the immediate, 1-week, and 3-month post-closure times. Further numerous comparisons of the occasions reveal that every pair differs considerably. F=444.425, P< 0.001 indicates that there is a significant difference between the 4 occurrences. Conclusions: Comparable positive effects are shown on hemodynamics, right heart dimensions, and functional capacity. Immediately upon device closure, the highest favourable effects on right cardiac functions, remodelling, of heart functions and the advantage is still there three months later.

 

 

 

Files

IJPCR,Vol15,Issue4,Article114.pdf

Files (359.9 kB)

Name Size Download all
md5:1fd75e4d8d2c4564844853d6c409100b
359.9 kB Preview Download

Additional details

Dates

Accepted
2023-03-20

References

  • 1. Interventional Cardiology Right ventricle reverse remodelling following transcatheter and surgical secundum : Atrial septal defect closure in adults by cardiac magnetic resonance imaging. 2021; 2(1):47–52. 2. Alkhateeb A, Roushdy A, Hasan-ali H, Kishk YT, Hassan AKM. The changes in biventricular remodelling and function after atrial septal defect device closure and its relation to age of closure. 2020; 2(1):1-7. 3. Prashant Kumar. Assessment of Ventricular Function in Patients of Atrial Septal Defect by Strain Imaging before and after Correction. 2019;2(3):41–6. 4. Chen Q, Sun X, Cao H, Zhang G, Chen L. Echocardiographic Evaluation of Changes in Cardiac Hemodynamics and Loading Conditions after Transthoracic Minimally Invasive Device Closure of Atrial Septal Defect. 2015;2(1):1–11. 5. Akula VS, Durgaprasad R, Velam V, Kasala L, Sc M, Rodda M, et al. Right Ventricle before and after Atrial Septal Defect Device Closure. 2016;1(2):1381– 8. 6. Tei C, Ling LH, Hodge DO, et al: New index of combined systolic and distolic myocardial performance: A simple and reproducible measure of cardiac function: A study in normal and dilated cardiomyopathy. J Cardiol. 1995; 26: 357–366 7. Agac MT, Aky uz AR, Acar Z, et al: Evaluation of right ventricular function in early period following transcatheter closure of atrial septal defect. Echocardiography. 2012;29:358–362. 8. Wu ET, Akagi T, Taniguchi M, et al: Differences in right and left ventricular remodeling after transcatheter closure of atrial septal defect among adults. Catheter Cardiovasc Interv. 2007; 69: 866–871. 9. Salehian O, Horlick E, Schwerzmann M, et al: Improvements in cardiac form and function after transcatheter closure of secundum atrial septal defects. J Am Coll Cardiol. 2005;45:499–504.