A Prospective Case Control Study of Maternal-Fetal Outcomes in Pregnant Women with Hyperemesis Gravidarum at Tertiary Care Hospital Tirupati
Authors/Creators
- 1. Postgraduate, Department of Obstetrics and Gynaecology, Sri Venkateswara Ramnarain Ruia Government General Hospital, Sri Venkateswara Medical College, Tirupati, Andhra Pradesh, India
- 2. Assistant Professor, Department of Obstetrics and Gynaecology, Sri Venkateswara Ramnarain Ruia Government General Hospital, Sri Venkateswara Medical College, Tirupati, Andhra Pradesh, India
- 3. Professor, Department of Obstetrics and Gynaecology, Sri Venkateswara Ramnarain Ruia Government General Hospital, Sri Venkateswara Medical College, Tirupati, Andhra Pradesh, India
Description
Background: One of the most common symptoms seen in pregnant women before the 20th week of pregnancy is nausea and vomiting; an exaggeration of these symptoms, known as hyperemesis gravidarum (HG), can lead to maternal and foetal catastrophes, as well as death. Aim: To investigate certain risk factors and maternal and foetal outcomes of Hyperemesis Gravidarum at Tirupati Tertiary Care Hospital. Methods: A prospective hospital-based case control observational study was conducted on 60 pregnant women with diagnosed HG and 60 pregnant women without HG as a control group. The prevalence of HG was found to be 2.8% among pregnant women in our study. The majority of these women (53.3%) were between the ages of 21 and 25. There is a strong association between hyperemesis gravidarum and preterm labour. There is an association between hyperemesis gravidarum and birth weight. There is a significant association between hyperemesis gravidarum and birth weight. Upper Lower & Lower socioeconomic status (66.6%), primigravida (71.7%), and BMI:18.5 (58.3%) were identified as important risk factors for developing HG. However, gestational age of less than 10 weeks (51.7%) was found to be less likely to be a risk for HG. Low birth weight (p=0.002), small for gestational age (p=0.02), IUGR (p=0.05), anaemia (p=0.04), maternal weight loss (p=0.002), ketonuria (p=0.01), and electrolyte imbalance (p=0.001) were all significantly associated with hyperemesis gravidarum. Conclusion: Hyperemesis gravidarum has a significant impact on maternal health. Multiparity and a history of HG are risk factors for developing the condition, which should be monitored in at-risk pregnant women so that early intervention can be implemented to avoid any negative outcomes.
Abstract (English)
Background: One of the most common symptoms seen in pregnant women before the 20th week of pregnancy is nausea and vomiting; an exaggeration of these symptoms, known as hyperemesis gravidarum (HG), can lead to maternal and foetal catastrophes, as well as death. Aim: To investigate certain risk factors and maternal and foetal outcomes of Hyperemesis Gravidarum at Tirupati Tertiary Care Hospital. Methods: A prospective hospital-based case control observational study was conducted on 60 pregnant women with diagnosed HG and 60 pregnant women without HG as a control group. The prevalence of HG was found to be 2.8% among pregnant women in our study. The majority of these women (53.3%) were between the ages of 21 and 25. There is a strong association between hyperemesis gravidarum and preterm labour. There is an association between hyperemesis gravidarum and birth weight. There is a significant association between hyperemesis gravidarum and birth weight. Upper Lower & Lower socioeconomic status (66.6%), primigravida (71.7%), and BMI:18.5 (58.3%) were identified as important risk factors for developing HG. However, gestational age of less than 10 weeks (51.7%) was found to be less likely to be a risk for HG. Low birth weight (p=0.002), small for gestational age (p=0.02), IUGR (p=0.05), anaemia (p=0.04), maternal weight loss (p=0.002), ketonuria (p=0.01), and electrolyte imbalance (p=0.001) were all significantly associated with hyperemesis gravidarum. Conclusion: Hyperemesis gravidarum has a significant impact on maternal health. Multiparity and a history of HG are risk factors for developing the condition, which should be monitored in at-risk pregnant women so that early intervention can be implemented to avoid any negative outcomes.
Files
IJPCR,Vol15,Issue4,Article12.pdf
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Additional details
Dates
- Accepted
-
2023-03-27
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/15/IJPCR,Vol15,Issue4,Article12.pdf
- Development Status
- Active
References
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