Phytochemical analysis, Antioxidant and Analgesic Activity of Acetone Extract of Curcuma Amada Roxb Rhizome
Authors/Creators
- 1. M M College of Pharmacy, Maharishi Markandshwar (Deemed To Be University), Mullana, Ambala-133207, Haryana, India
Description
Curcuma amada Roxb., often known as amba haldi, is a highly rhizomatic aromatic herb that contains a number of phytoconstituents. This study was done to investigate the antioxidant and analgesic properties of C. amada acetone extract. In-vitro antioxidant activity was assessed using the DPPH (2, 2-Diphenyl-1-picrylhydrazyl) free radical scavenging assay and the nitric oxide scavenging assay, while in-vivo analgesic activity was assessed using the tail flick method and the formalin induced pain test in male wistar rats weighing 150–200 gm at different doses (100 mg/kg, 200 mg/kg, and 400 mg/kg). According to the findings, the acetone extract of C. amada had antioxidant and analgesic efficacy at all three doses of 100 mg/kg, 200 mg/kg, and 400 mg/kg as compared to the control group. C. amada acetone extract exhibited in-vitro antioxidant as well as in-vivo analgesic activity in experimental animals.
Abstract (English)
Curcuma amada Roxb., often known as amba haldi, is a highly rhizomatic aromatic herb that contains a number of phytoconstituents. This study was done to investigate the antioxidant and analgesic properties of C. amada acetone extract. In-vitro antioxidant activity was assessed using the DPPH (2, 2-Diphenyl-1-picrylhydrazyl) free radical scavenging assay and the nitric oxide scavenging assay, while in-vivo analgesic activity was assessed using the tail flick method and the formalin induced pain test in male wistar rats weighing 150–200 gm at different doses (100 mg/kg, 200 mg/kg, and 400 mg/kg). According to the findings, the acetone extract of C. amada had antioxidant and analgesic efficacy at all three doses of 100 mg/kg, 200 mg/kg, and 400 mg/kg as compared to the control group. C. amada acetone extract exhibited in-vitro antioxidant as well as in-vivo analgesic activity in experimental animals.
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IJTPR,Vol11,Issue5,Article6.pdf
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Additional details
Dates
- Accepted
-
2021-10-15
Software
References
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