A Comparative Study between Intravenous Lignocaine and Intravenous Paracetamol for Postoperative Analgesia in Exploratory Laparotomy

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Abstract (English)

Abstract
Aim: The aim of the present study was to assess the impact of intravenous lignocaine and
intravenous paracetamol on intra-operative hemodynamics, post-op pain scores, and post-op
analgesic requirement in patients undergoing exploratory laparotomy.
Methods: This randomized single-blinded observational study was conducted in The
Department of Anaesthesiology, critical care, and pain management at SRMS Institute of
Medical Sciences, Bareilly, after obtaining prior approval from the ethical committee and
after written, informed consent was obtained from the patient. The study was conducted from
1st Feb 21 to 31st July 22. The sample size for this study was 72 patients i.e., 36 patients in
each group.
Results: The mean ± SD of age (years) in group I was 38.42 ± 10.8 and in group, II was
37.86 ± 10.62 with no significant difference between them. No significant difference was
seen in weight (kg) (p value=0.448), height (cm) (p value=0.75), and body mass index
(kg/m²)(p value=0.739) between group I and group II. Mean ± SD of weight (kg), height
(cm), body mass index (kg/m²) in group I was 61.06 ± 5.82, 161.61 ± 7.34, 23.78 ± 2.33
respectively and in group II was 62.19 ± 6.82, 161.08 ± 6.66, 23.96 ± 2.09 respectively with
no significant difference between them. No significant difference was seen in heart rate,
systolic, diastolic blood pressure, VAS scores and SPO2.
Conclusion: The present study demonstrated lignocaine as a superior analgesic drug with
context to paracetamol for postoperative pain relief in an exploratory laparotomy